WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0008568 microtubule severing ATPase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

9 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  contributes_to
  contributes_to
  contributes_to
  enables
  enables
  enables
  enables

24 Parents

Identifier Name Description
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0007017 microtubule-based process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
GO:0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
GO:0000226 microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0016887 ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0140657 ATP-dependent activity A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.
GO:0120544 polypeptide conformation or assembly isomerase activity Catalysis of a reaction that alters the conformation or assembly of a polypeptide.
GO:0016853 isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
GO:0120543 macromolecular conformation isomerase activity Catalysis of a reaction that alters the macromolecular conformation of a molecule.
GO:0140776 protein-containing complex destabilizing activity A molecular function that involves direct binding to one of the subunits of a protein-containing complex and promoting the dissociation of one or many subunits. This often happens by changing the conformation of the protein being bound, which decreases its affinity for the rest of the complex.
GO:0170060 microtubule destabilizing activity A protein-containing complex destabilizing activity that promotes microtubule catastrophe (transition from microtubule growth to microtubule shrinkage).
GO:0008568 microtubule severing ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.

25 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0170060 GO:0008568
is_a GO:0140096 GO:0008568
is_a GO:0140657 GO:0008568
is_a GO:0120544 GO:0008568
part of GO:0000226 GO:0008568
is_a GO:0016853 GO:0008568
has part GO:0016787 GO:0008568
has part GO:0016887 GO:0008568
part of GO:0016043 GO:0008568
part of GO:0071840 GO:0008568
has part GO:0016817 GO:0008568
has part GO:0016818 GO:0008568
is_a GO:0003824 GO:0008568
part of GO:0008150 GO:0008568
part of GO:0007010 GO:0008568
has part GO:0003674 GO:0008568
is_a GO:0003674 GO:0008568
has part GO:0016462 GO:0008568
has part GO:0017111 GO:0008568
part of GO:0006996 GO:0008568
is_a GO:0140776 GO:0008568
is_a GO:0120543 GO:0008568
has part GO:0003824 GO:0008568
part of GO:0009987 GO:0008568
part of GO:0007017 GO:0008568

3 Synonyms

Name Type
ATP phosphohydrolase (tubulin-dimerizing) synonym
microtubule-severing ATPase activity synonym
katanin activity synonym