WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0034979 NAD-dependent protein lysine deacetylase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: N(6)-acetyl-L-lysyl-[protein] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a protein to NAD, producing nicotinamide.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

11 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables
  enables

9 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0016746 acyltransferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
GO:0160215 deacylase activity Catalysis of the reaction: R-CO-X + H2O = R-COOH + HX, hydrolysis of an acyl group or groups from a substrate molecule.
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
GO:0034979 NAD-dependent protein lysine deacetylase activity Catalysis of the reaction: N(6)-acetyl-L-lysyl-[protein] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a protein to NAD, producing nicotinamide.
GO:0141218 NAD-dependent protein lysine deacylase activity Catalysis of the reaction: N6-acyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-acyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].

16 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0034979 GO:0017136
is_a GO:0034979 GO:0032041
is_a GO:0141218 GO:0034979
is_a GO:0016740 GO:0034979
is_a GO:0003674 GO:0034979
is_a GO:0140096 GO:0034979
is_a GO:0003824 GO:0034979
is_a GO:0160215 GO:0034979
is_a GO:0016746 GO:0034979
is_a GO:0016747 GO:0034979
is_a GO:0034979 GO:0046969
is_a GO:0034979 GO:0046970
is_a GO:0034979 GO:0097372
is_a GO:0034979 GO:0140765
is_a GO:0034979 GO:0141208
is_a GO:0034979 GO:0141222

6 Synonyms

Name Type
NAD(+)-dependent protein deacetylase synonym
NAD-dependent protein deacetylase activity synonym
NAD(+)-dependent protein deacylase synonym
protein lysine deacetylase synonym
protein acetyllysine N-acetyltransferase synonym
protein lysine deacylase synonym