15 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0003674 | molecular_function | A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
| GO:0003824 | catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
| GO:0016740 | transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
| GO:0140096 | catalytic activity, acting on a protein | Catalytic activity that acts to modify a protein. |
| GO:0016746 | acyltransferase activity | Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). |
| GO:0019213 | deacetylase activity | Catalysis of the hydrolysis of an acetyl group from a substrate molecule. |
| GO:0160215 | deacylase activity | Catalysis of the reaction: R-CO-X + H2O = R-COOH + HX, hydrolysis of an acyl group or groups from a substrate molecule. |
| GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor). |
| GO:0033558 | protein lysine deacetylase activity | Catalysis of the reaction: Removal of an acetyl group from a lysine residue in a protein. |
| GO:0004407 | histone deacetylase activity | Removal of an acetyl group from a lysine residue in a histone. |
| GO:0034979 | NAD-dependent protein lysine deacetylase activity | Catalysis of the reaction: N(6)-acetyl-L-lysyl-[protein] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a protein to NAD, producing nicotinamide. |
| GO:0017136 | histone deacetylase activity, NAD-dependent | Catalysis of the reaction: N(6)-acetyl-L-lysyl-[histone] + NAD+ + H2O = L-lysyl-[protein] + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a histone to NAD, producing nicotinamide. |
| GO:0141218 | NAD-dependent protein lysine deacylase activity | Catalysis of the reaction: N6-acyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-acyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]. |
| GO:0141050 | histone H3K deacetylase activity | Removal of an acetyl group from a lysine residue in a histone H3. |
| GO:0032041 | histone H3K14 deacetylase activity, NAD-dependent | Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + NAD+ + H2O = histone H3 L-lysine (position 14) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K14 to NAD, producing nicotinamide. |
14 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0017136 | GO:0032041 |
| is_a | GO:0141050 | GO:0032041 |
| is_a | GO:0019213 | GO:0032041 |
| is_a | GO:0004407 | GO:0032041 |
| is_a | GO:0141218 | GO:0032041 |
| is_a | GO:0003824 | GO:0032041 |
| is_a | GO:0160215 | GO:0032041 |
| is_a | GO:0140096 | GO:0032041 |
| is_a | GO:0034979 | GO:0032041 |
| is_a | GO:0016740 | GO:0032041 |
| is_a | GO:0033558 | GO:0032041 |
| is_a | GO:0016747 | GO:0032041 |
| is_a | GO:0016746 | GO:0032041 |
| is_a | GO:0003674 | GO:0032041 |
