WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0019785 ISG15-specific peptidase activity GO

Namespace  molecular_function Obsolete  false
Description  A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

8 Parents

Identifier Name Description
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
GO:0019783 ubiquitin-like protein peptidase activity An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.
GO:0019785 ISG15-specific peptidase activity A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.

7 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0019783 GO:0019785
is_a GO:0008234 GO:0019785
is_a GO:0016787 GO:0019785
is_a GO:0003674 GO:0019785
is_a GO:0003824 GO:0019785
is_a GO:0008233 GO:0019785
is_a GO:0140096 GO:0019785

1 Synonyms

Name Type
ISG15-specific protease activity synonym