WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0033749 histone H4R3 demethylase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

1 Ontology Annotations

Annotation Extension Qualifier
  enables

19 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0006325 chromatin organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.
GO:0006338 chromatin remodeling A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
GO:0051213 dioxygenase activity Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.
GO:0016706 2-oxoglutarate-dependent dioxygenase activity Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.
GO:0140993 histone modifying activity A catalytic activity that acts on a histone protein. Reversible histone modifications contribute to regulation of gene expression.
GO:0032451 demethylase activity Catalysis of the removal of a methyl group from a substrate.
GO:0140457 protein demethylase activity Catalysis of the removal of a methyl group from a protein.
GO:0032452 histone demethylase activity Catalysis of the removal of a methyl group from a histone.
GO:0141058 histone H4 demethylase activity Catalysis of the removal of a methyl group from a modified lysine residue of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
GO:0033749 histone H4R3 demethylase activity Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.

18 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0141058 GO:0033749
is_a GO:0016706 GO:0033749
part of GO:0006325 GO:0033749
part of GO:0009987 GO:0033749
part of GO:0006338 GO:0033749
is_a GO:0140096 GO:0033749
is_a GO:0051213 GO:0033749
is_a GO:0016705 GO:0033749
is_a GO:0140993 GO:0033749
is_a GO:0140457 GO:0033749
is_a GO:0032452 GO:0033749
part of GO:0008150 GO:0033749
is_a GO:0032451 GO:0033749
is_a GO:0003824 GO:0033749
is_a GO:0016491 GO:0033749
is_a GO:0003674 GO:0033749
part of GO:0016043 GO:0033749
part of GO:0071840 GO:0033749

3 Synonyms

Name Type
histone H4-methyl-arginine-3 demethylase activity synonym
histone H4R3me demethylase activity synonym
histone demethylase activity (H4-R3 specific) synonym