WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0001649 Fluorouracil resistant

Description  Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals.

5 RNAi

WormBase ID
WBRNAi00097781
WBRNAi00097782
WBRNAi00081723
WBRNAi00081718
WBRNAi00081721

7 RNAi Not Observed

WormBase ID
WBRNAi00110190
WBRNAi00081715
WBRNAi00081717
WBRNAi00081716
WBRNAi00081719
WBRNAi00081720
WBRNAi00081722

2 Children

Identifier Name Description
WBPhenotype:0001650 germ cell death response to 5 FU resistant Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei.
WBPhenotype:0001651 growth arrest response to 5 FU resistant Animals grow well during or after exposure to 5-FU under conditions where control animals are growth inhibited.

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Parents

Identifier Name Description
WBPhenotype:0001502 chemical resistant Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.
WBPhenotype:0000011 drug resistant Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug.

18 Phenotype Allele

Public Name
jg14
jg18
jg17
jg16
jg15
jg22
jg21
jg20
jg19
jg12
jg11
jg3
jg2
jg1
jg10
jg9
jg8
jg7

0 Phenotype Allele Not Observed

1 Synonyms

Name Type
5 FU resistant