WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0046222 aflatoxin metabolic process GO

Namespace  biological_process Obsolete  false
Description  The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

7 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0019748 secondary metabolic process The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
GO:0009404 toxin metabolic process The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:0043385 mycotoxin metabolic process The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.
GO:0046222 aflatoxin metabolic process The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.

16 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046222 GO:0045122
is_a GO:0043385 GO:0046222
is_a GO:0008152 GO:0046222
is_a GO:0008150 GO:0046222
is_a GO:0019748 GO:0046222
is_a GO:0009404 GO:0046222
is_a GO:0009987 GO:0046222
is_a GO:0046222 GO:0046223
part of GO:0046222 GO:0052807
part of GO:0046222 GO:0140395
part of GO:0046222 GO:0140399
regulates GO:0046222 GO:1900177
regulates GO:0046222 GO:1900178
negatively regulates GO:0046222 GO:1900178
positively regulates GO:0046222 GO:1900179
regulates GO:0046222 GO:1900179

9 Synonyms

Name Type
aflatoxin B metabolic process synonym
aflatoxin B1 metabolism synonym
aflatoxin B1 metabolic process synonym
aflatoxin B2 metabolism synonym
aflatoxin B2 metabolic process synonym
GO:0043389 alt_id
aflatoxin metabolism synonym
GO:0043391 alt_id
GO:0043390 alt_id