WormMine: Gene WBGene00228763

• WormBase Gene ID: WBGene00228763
• Gene Name: Bm8502
• Sequence Name: Bm8502
• Organism: Brugia malayi
• Automated Description: Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: Histidine phosphatase superfamily, clade-2; Histidine phosphatase superfamily (branch 2); and Histidine phosphatase superfamily. Is an ortholog of O. volvulus OVOC12067.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm8502.1	Bm8502.1		[unknown]

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm8502	Bm8502		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

14 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M30
	Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M42_vs_M30
	Transcripts that showed significantly lower expression in L3 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L3_vs_Adult_Downregulated
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M42
	Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F120_vs_F30
	Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Micro_Downregulated
	Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F120_vs_F42
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_F120
	Transcripts that showed significantly lower expression in L4 larva comparing to in adult.	edgeR v3.28. FDR < 0.05, fold change > 2.	WBPaper00061765:L4_vs_Adult_Downregulated
	Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone.	An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed.	WBPaper00049261:20-hydroxyecdysone_upregulated_protein
	Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to female B. malayi 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M42_vs_F42
	Transcripts that showed significantly decreased expression at infective lava stage 3 (iL3) (from mosquitoes), comparing to L3 Day 9 worms.	Differential gene expression analysis was performed using both DESeq and EdgeR, and the overlapping genes with FDR<0.01 were retained.	WBPaper00059852:B.malayi_iL3_stage_downregulated_vs_L3Day9
	Transcripts that showed significantly decreased expression at infective lava stage 3 (iL3) (from mosquitoes), comparing to L4 worms.	Differential gene expression analysis was performed using both DESeq and EdgeR, and the overlapping genes with FDR<0.01 were retained.	WBPaper00059852:B.malayi_iL3_stage_downregulated_vs_L4
	Transcripts that showed significantly decreased expression at infective lava stage 3 (iL3) (from mosquitoes), comparing to L3 Day 6 worms.	Differential gene expression analysis was performed using both DESeq and EdgeR, and the overlapping genes with FDR<0.01 were retained.	WBPaper00059852:B.malayi_iL3_stage_downregulated_vs_L3Day6

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term