WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00230001 Gene Name  Bma-pqn-27
Sequence Name  ? Bm9740 Organism  Brugia malayi
Automated Description  Enriched in female based on proteomic studies. Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domain: Armadillo-type fold. Is an ortholog of C. elegans pqn-27. Biotype  SO:0001217
Genetic Position 
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm9740a.1 Bm9740a.1   [unknown]
Transcript:Bm9740b.1 Bm9740b.1   [unknown]
 

Other

2 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm9740a Bm9740a   [unknown]
CDS:Bm9740b Bm9740b   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

Name URL
WormBaseAcedbConverter  

0 Downstream Intergenic Region

10 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M120_vs_F120
  Transcripts that showed significantly lower expression in adult comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:Adult_vs_Micro_Downregulated
  Transcripts that showed significantly higher expression in L3 larva comparing to in adult. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L3_vs_Adult_Upregulated
  Transcripts that showed significantly higher expression in L4 larva comparing to in adult. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L4_vs_Adult_Upregulated
  Transcripts that showed significantly decreased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_F120_vs_F30
  Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_M120_vs_M42
  Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone. An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed. WBPaper00049261:20-hydroxyecdysone_upregulated_protein
  Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. WBPaper00045439:BM_Cluster_P4
  Transcripts that showed significantly decreased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_F30_vs_L4
  Proteins that were enriched in female animals. Criteria used for protein identification included: two or more peptide matches, MASCOT score > 60, and P < 0.05. WBPaper00041323:female-associated

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term