WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Strain :

WormBase ID  WBStrain00055593 CGC Received  2023-08-23
Genotype  unc-73(e936az30) dxbp-1(az121) I; smg-4(az152) V. Laboratory  CGC
Made By  WBPerson713 Mutagen  CRISPR_Cas9
Name  SZ345 Outcrossed  x2
Remark  dxbp-1(az121) is a K23N mutation that promotes usage of introns starting in UU when the sequence GUU is present at the 5' end of the intron. az121 was initially identified as able to suppress uncoordination of unc-73(e936) by promoting a cryptic splice site that defines an intron beginning UU. smg-4 mutant background allows for high throughput sequencing to identify frame shifted transcripts since it can move the 5'ss over by 1nt. e936az30 has no phenotype on its own, but it offers two adjacent cryptic 5'ss separated by 1nt. Reference: Suzuki JMNGL, et al. PLoS Genet. 2022 Feb 10;18(2):e1010028. doi: 10.1371/journal.pgen.1010028. PMID: 35143478. Species  Caenorhabditis elegans

4 Alleles

Public Name
e936
az152
az121
 

1 Data Sets

Name URL
WormBaseAcedbConverter  

3 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004882 smg-4 F46B6.3 Caenorhabditis elegans
WBGene00006805 unc-73 F55C7.7 Caenorhabditis elegans
WBGene00013128 dxbp-1 Y52B11A.9 Caenorhabditis elegans