WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0061763 multivesicular body-lysosome fusion GO

Namespace  biological_process Obsolete  false
Description  The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

30 Parents

Identifier Name Description
GO:0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0051234 establishment of localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.
GO:0007033 vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
GO:0051649 establishment of localization in cell Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
GO:0051641 cellular localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
GO:0046907 intracellular transport The directed movement of substances within a cell.
GO:0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
GO:0016192 vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
GO:0090174 organelle membrane fusion The joining of two lipid bilayers to form a single organelle membrane.
GO:0048284 organelle fusion The creation of a single organelle from two or more organelles.
GO:0061025 membrane fusion The membrane organization process that joins two lipid bilayers to form a single membrane.
GO:0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
GO:0007040 lysosome organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
GO:0080171 lytic vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
GO:0006906 vesicle fusion Fusion of the membrane of a transport vesicle with its target membrane.
GO:0007041 lysosomal transport The directed movement of substances into, out of or within a lysosome.
GO:0007034 vacuolar transport The directed movement of substances into, out of or within a vacuole.
GO:0008333 endosome to lysosome transport The directed movement of substances from endosomes to lysosomes.
GO:0016197 endosomal transport The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.
GO:0032509 endosome transport via multivesicular body sorting pathway The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
GO:0071985 multivesicular body sorting pathway A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded.
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.
GO:0097212 lysosomal membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
GO:0061763 multivesicular body-lysosome fusion The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.

34 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0097212 GO:0061763
part of GO:0032510 GO:0061763
is_a GO:0006906 GO:0061763
part of GO:0051649 GO:0061763
part of GO:0016043 GO:0061763
is_a GO:0048284 GO:0061763
part of GO:0080171 GO:0061763
part of GO:0032509 GO:0061763
is_a GO:0071840 GO:0061763
is_a GO:0016043 GO:0061763
part of GO:0009987 GO:0061763
part of GO:0008333 GO:0061763
part of GO:0051641 GO:0061763
part of GO:0006810 GO:0061763
part of GO:0006996 GO:0061763
part of GO:0016192 GO:0061763
is_a GO:0061025 GO:0061763
is_a GO:0061024 GO:0061763
part of GO:0071840 GO:0061763
part of GO:0016197 GO:0061763
is_a GO:0009987 GO:0061763
part of GO:0071985 GO:0061763
part of GO:0008150 GO:0061763
part of GO:0007041 GO:0061763
part of GO:0007040 GO:0061763
part of GO:0007034 GO:0061763
part of GO:0007033 GO:0061763
is_a GO:0016050 GO:0061763
is_a GO:0090174 GO:0061763
part of GO:0051234 GO:0061763

5 Synonyms

Name Type
fusion of multivesicular body to lysosome synonym
fusion of MVB to lysosome synonym
late endosome-lysosome fusion synonym
MVB-lysosome fusion synonym
endosome-lysosome fusion synonym