28 Parents
| Identifier | Name | Description |
|---|---|---|
| GO:0009987 | cellular process | Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
| GO:0008150 | biological_process | A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
| GO:0071840 | cellular component organization or biogenesis | A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. |
| GO:0016043 | cellular component organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. |
| GO:0003674 | molecular_function | A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
| GO:0032991 | protein-containing complex | A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. |
| GO:0005575 | cellular_component | A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). |
| GO:0005622 | intracellular anatomical structure | A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. |
| GO:0110165 | cellular anatomical structure | A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. |
| GO:0005488 | binding | The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
| GO:0043226 | organelle | Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. |
| GO:0043229 | intracellular organelle | Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. |
| GO:0043228 | membraneless organelle | Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. |
| GO:0043232 | intracellular membraneless organelle | Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. |
| GO:0000785 | chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
| GO:0005694 | chromosome | A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. |
| GO:0005515 | protein binding | Binding to a protein. |
| GO:0006325 | chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| GO:0042393 | histone binding | Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription. |
| GO:0032993 | protein-DNA complex | A macromolecular complex containing both protein and DNA molecules. |
| GO:0000786 | nucleosome | A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures. |
| GO:0030674 | protein-macromolecule adaptor activity | An adaptor activity that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid. |
| GO:0060090 | molecular adaptor activity | The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way. |
| GO:0003682 | chromatin binding | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
| GO:0140006 | histone H3 reader activity | A histone reader that specifically binds either to an unmodified histone H3 or a form modified by a post-translational modification on a specific residue. The most common PTMs on histones are methylation, acetylation and phosphorylation. |
| GO:0140463 | chromatin-protein adaptor activity | An adaptor activity that brings together a protein and a region of the chromatin, such as a nucleosome, to establish or maintain the chromatin localization of the protein, or the complex to which it belongs. |
| GO:0140566 | histone reader activity | A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery. |
| GO:0062072 | histone H3K9me2/3 reader activity | A histone reader that recognizes a histone H3 trimethylated at lysine 9. In some organisms, there is only H3K9me2, not H3K9me3, but this modification is recognized by homologous readers. |
28 Relations
| Relationship |
Parent Term . Identifier |
Child Term . Identifier |
|---|---|---|
| is_a | GO:0140006 | GO:0062072 |
| is_a | GO:0003674 | GO:0062072 |
| occurs in | GO:0043226 | GO:0062072 |
| is_a | GO:0030674 | GO:0062072 |
| is_a | GO:0140566 | GO:0062072 |
| is_a | GO:0060090 | GO:0062072 |
| has part | GO:0003674 | GO:0062072 |
| part of | GO:0006325 | GO:0062072 |
| has part | GO:0005515 | GO:0062072 |
| occurs in | GO:0032993 | GO:0062072 |
| is_a | GO:0140463 | GO:0062072 |
| occurs in | GO:0005575 | GO:0062072 |
| occurs in | GO:0032991 | GO:0062072 |
| occurs in | GO:0005694 | GO:0062072 |
| occurs in | GO:0000786 | GO:0062072 |
| occurs in | GO:0000785 | GO:0062072 |
| occurs in | GO:0043232 | GO:0062072 |
| has part | GO:0042393 | GO:0062072 |
| part of | GO:0008150 | GO:0062072 |
| part of | GO:0009987 | GO:0062072 |
| has part | GO:0003682 | GO:0062072 |
| has part | GO:0005488 | GO:0062072 |
| occurs in | GO:0043229 | GO:0062072 |
| part of | GO:0016043 | GO:0062072 |
| occurs in | GO:0005622 | GO:0062072 |
| occurs in | GO:0043228 | GO:0062072 |
| occurs in | GO:0110165 | GO:0062072 |
| part of | GO:0071840 | GO:0062072 |
