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GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0140640
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catalytic activity, acting on a nucleic acid
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Catalytic activity that acts to modify a nucleic acid. |
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GO:0140097
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catalytic activity, acting on DNA
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Catalytic activity that acts to modify DNA. |
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GO:0016787
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hydrolase activity
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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
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GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
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GO:0016817
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hydrolase activity, acting on acid anhydrides
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Catalysis of the hydrolysis of any acid anhydride. |
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GO:0016818
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hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
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Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. |
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GO:0016462
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pyrophosphatase activity
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Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. |
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GO:0017111
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ribonucleoside triphosphate phosphatase activity
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Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. |
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GO:0016887
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ATP hydrolysis activity
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Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
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GO:0140657
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ATP-dependent activity
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A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. |
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GO:0003676
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nucleic acid binding
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Binding to a nucleic acid. |
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GO:0005515
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protein binding
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Binding to a protein. |
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GO:0140299
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molecular sensor activity
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Binding to a molecule and eliciting a change in the protein's activity in response to the intracellular level of that molecule. |
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GO:0098772
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molecular function regulator activity
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A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. |
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GO:0003677
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DNA binding
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Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
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GO:0008094
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ATP-dependent activity, acting on DNA
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Catalytic activity that acts to modify DNA, driven by ATP hydrolysis. |
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GO:0003684
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damaged DNA binding
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Binding to damaged DNA. |
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GO:0140612
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DNA damage sensor activity
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A molecule that recognises toxic DNA structures, for example, double-strand breaks or collapsed replication forks, and initiates a signaling response. |
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GO:0140664
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ATP-dependent DNA damage sensor activity
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A molecule that recognises toxic DNA structures, and initiates a signaling response, driven by ATP hydrolysis. |
