WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:0140941 histone H4K20me methyltransferase activity GO

Namespace  molecular_function Obsolete  false
Description  Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethlyated lysine residue at position 20 of histone H4, producing H4K20me2.

0 Cross References

1 Data Sets

Name URL
GO Annotation data set  

1 Ontology

Name
GO

3 Ontology Annotations

Annotation Extension Qualifier
  enables
  enables
  enables

22 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0016043 cellular component organization A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016740 transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0008170 N-methyltransferase activity Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.
GO:0016741 transferase activity, transferring one-carbon groups Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0006325 chromatin organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.
GO:0006338 chromatin remodeling A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
GO:0016279 protein-lysine N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
GO:0016278 lysine N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.
GO:0008276 protein methyltransferase activity Catalysis of the transfer of a methyl group (CH3-) to a protein.
GO:0140993 histone modifying activity A catalytic activity that acts on a histone protein. Reversible histone modifications contribute to regulation of gene expression.
GO:0042054 histone methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or a lysine residue.
GO:0140939 histone H4 methyltransferase activity Catalysis of the reaction: Catalysis of the reaction: S-adenosyl-L-methionine + a histone H4 = S-adenosyl-L-homocysteine + a methylated histone H4. Histone methylation generally occurs on either an arginine or a lysine residue.
GO:0042799 histone H4K20 methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group to the lysine residue at position 20 of the histone H4 protein.
GO:0140941 histone H4K20me methyltransferase activity Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethlyated lysine residue at position 20 of histone H4, producing H4K20me2.

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0042799 GO:0140941
is_a GO:0016279 GO:0140941
is_a GO:0016741 GO:0140941
part of GO:0006338 GO:0140941
part of GO:0006325 GO:0140941
is_a GO:0016278 GO:0140941
is_a GO:0016740 GO:0140941
is_a GO:0008276 GO:0140941
is_a GO:0140096 GO:0140941
is_a GO:0042054 GO:0140941
is_a GO:0140993 GO:0140941
part of GO:0009987 GO:0140941
is_a GO:0008170 GO:0140941
part of GO:0008150 GO:0140941
is_a GO:0003674 GO:0140941
is_a GO:0140939 GO:0140941
is_a GO:0008168 GO:0140941
is_a GO:0003824 GO:0140941
part of GO:0016043 GO:0140941
is_a GO:0008757 GO:0140941
part of GO:0071840 GO:0140941

4 Synonyms

Name Type
histone H4K20 dimethylation synonym
histone H4K20me methylase activity synonym
histone H4 methyl lysine(20) N-methyltransferase activity (H4-K20 specific) synonym
histone H4-K20 dimethylation synonym