WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process GO

Namespace  molecular_function Obsolete  false
Description  Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

17 Parents

Identifier Name Description
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a protein. Includes protein modification.
GO:0140096 catalytic activity, acting on a protein Catalytic activity that acts to modify a protein.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0004175 endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
GO:0070001 aspartic-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
GO:0004190 aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
GO:0042987 amyloid precursor protein catabolic process The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.
GO:0042982 amyloid precursor protein metabolic process The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.
GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process.

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0004190 GO:1902944
part of GO:0042987 GO:1902944
part of GO:0042987 GO:1902944
is_a GO:0004190 GO:1902944
part of GO:0043170 GO:1902944
is_a GO:0016787 GO:1902944
is_a GO:0003824 GO:1902944
is_a GO:0140096 GO:1902944
is_a GO:0070001 GO:1902944
part of GO:0019538 GO:1902944
part of GO:0008150 GO:1902944
is_a GO:0003674 GO:1902944
part of GO:0042982 GO:1902944
part of GO:0008152 GO:1902944
is_a GO:0004175 GO:1902944
is_a GO:0008233 GO:1902944
part of GO:0044238 GO:1902944
part of GO:0009987 GO:1902944
negatively regulates GO:1902944 GO:1902960
negatively regulates GO:1902944 GO:1902960
positively regulates GO:1902944 GO:1902961
positively regulates GO:1902944 GO:1902961

35 Synonyms

Name Type
carboxyl protease activity involved in amyloid precursor protein breakdown synonym
aspartyl protease activity involved in APP catabolism synonym
carboxyl protease activity involved in amyloid precursor protein catabolism synonym
carboxyl protease activity involved in amyloid precursor protein catabolic process synonym
carboxyl protease activity involved in APP catabolic process synonym
carboxyl protease activity involved in amyloid precursor protein degradation synonym
carboxyl protease activity involved in APP catabolism synonym
aspartate protease activity involved in amyloid precursor protein catabolic process synonym
aspartate protease activity involved in amyloid precursor protein breakdown synonym
aspartate protease activity involved in amyloid precursor protein degradation synonym
aspartate protease activity involved in amyloid precursor protein catabolism synonym
aspartate protease activity involved in APP catabolism synonym
aspartate protease activity involved in APP catabolic process synonym
aspartic endopeptidase activity involved in amyloid precursor protein catabolic process synonym
aspartic endopeptidase activity involved in amyloid precursor protein breakdown synonym
aspartic endopeptidase activity involved in amyloid precursor protein degradation synonym
aspartic endopeptidase activity involved in amyloid precursor protein catabolism synonym
aspartic endopeptidase activity involved in APP catabolism synonym
aspartic endopeptidase activity involved in APP catabolic process synonym
aspartic protease activity involved in amyloid precursor protein catabolic process synonym
aspartic protease activity involved in amyloid precursor protein breakdown synonym
aspartic protease activity involved in amyloid precursor protein degradation synonym
aspartic protease activity involved in amyloid precursor protein catabolism synonym
aspartic protease activity involved in APP catabolism synonym
aspartic protease activity involved in APP catabolic process synonym
aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism synonym
aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown synonym
aspartic-type endopeptidase activity involved in APP catabolic process synonym
aspartic-type endopeptidase activity involved in amyloid precursor protein degradation synonym
aspartyl protease activity involved in amyloid precursor protein breakdown synonym