GO:0008150
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biological_process
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A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
GO:0003676
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nucleic acid binding
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Binding to a nucleic acid. |
GO:0065009
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regulation of molecular function
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Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
GO:1990837
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sequence-specific double-stranded DNA binding
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Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding. |
GO:0003677
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DNA binding
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Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0003690
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double-stranded DNA binding
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Binding to double-stranded DNA. |
GO:0043565
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sequence-specific DNA binding
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Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
GO:0001067
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transcription regulatory region nucleic acid binding
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Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair. |
GO:0000976
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transcription cis-regulatory region binding
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Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
GO:0001046
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core promoter sequence-specific DNA binding
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Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon. |
GO:0044092
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negative regulation of molecular function
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Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
GO:0051100
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negative regulation of binding
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Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. |
GO:0051098
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regulation of binding
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Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. |
GO:0051101
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regulation of DNA binding
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Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). |
GO:0043392
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negative regulation of DNA binding
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Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). |
GO:2000677
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regulation of transcription regulatory region DNA binding
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Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding. |
GO:2000678
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negative regulation of transcription regulatory region DNA binding
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Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding. |
GO:1904797
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negative regulation of core promoter binding
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Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding. |