WormMine: Phenotype WBPhenotype:0000193 dominant negative enzyme

• Description: Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype.

0 RNAi

0 RNAi Not Observed

0 Children

1 Data Sets

• WormBaseAcedbConverter

1 Parents

Identifier	Name	Description
WBPhenotype:0000727	enzyme activity variant	Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component).

0 Phenotype Allele

0 Phenotype Allele Not Observed

0 Synonyms