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GO:0008150
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biological_process
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A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
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GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0140640
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catalytic activity, acting on a nucleic acid
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Catalytic activity that acts to modify a nucleic acid. |
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GO:0140097
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catalytic activity, acting on DNA
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Catalytic activity that acts to modify DNA. |
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GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
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GO:0140657
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ATP-dependent activity
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A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. |
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GO:0050790
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regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
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GO:0065009
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regulation of molecular function
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Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
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GO:0016853
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isomerase activity
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Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. |
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GO:0120543
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macromolecular conformation isomerase activity
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Catalysis of a reaction that alters the macromolecular conformation of a molecule. |
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GO:0008094
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ATP-dependent activity, acting on DNA
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Catalytic activity that acts to modify DNA, driven by ATP hydrolysis. |
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GO:0120545
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nucleic acid conformation isomerase activity
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Catalysis of a reaction that alters the conformation of a nucleic acid. |
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GO:0003916
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DNA topoisomerase activity
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Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA. |
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GO:0003918
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DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
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Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2. |
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GO:0043085
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positive regulation of catalytic activity
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Any process that activates or increases the activity of an enzyme. |
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GO:0044093
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positive regulation of molecular function
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Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
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GO:0043462
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regulation of ATP-dependent activity
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Any process that modulates the rate of an ATP-dependent activity. |
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GO:0032781
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positive regulation of ATP-dependent activity
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Any process that activates or increases the rate of an ATP-dependent activity. |
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GO:2000373
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positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
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Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity. |
