WormMine

WS297

Intermine data mining platform for C. elegans and related nematodes

GO Term : GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity GO

Namespace  biological_process Obsolete  false
Description  Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.

0 Cross References

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

23 Parents

Identifier Name Description
GO:0008150 biological_process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
GO:0003674 molecular_function A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride.
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
GO:0016462 pyrophosphatase activity Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups.
GO:0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.
GO:0050790 regulation of catalytic activity Any process that modulates the activity of an enzyme.
GO:0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
GO:0098772 molecular function regulator activity A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
GO:0030234 enzyme regulator activity Binds to and modulates the activity of an enzyme.
GO:0003924 GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
GO:0005085 guanyl-nucleotide exchange factor activity Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.
GO:0030695 GTPase regulator activity Binds to and modulates the activity of a GTPase.
GO:0060589 nucleoside-triphosphatase regulator activity Binds to and modulates the activity of an NTPase.
GO:0051336 regulation of hydrolase activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0051098 regulation of binding Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
GO:0043087 regulation of GTPase activity Any process that modulates the rate of GTP hydrolysis by a GTPase.
GO:1905097 regulation of guanyl-nucleotide exchange factor activity Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.

22 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:1905097 GO:2001106
is_a GO:0008150 GO:2001106
regulates GO:0016787 GO:2001106
regulates GO:0060589 GO:2001106
is_a GO:0065009 GO:2001106
is_a GO:0065007 GO:2001106
regulates GO:0005488 GO:2001106
is_a GO:0043087 GO:2001106
regulates GO:0016817 GO:2001106
regulates GO:0005085 GO:2001106
regulates GO:0016818 GO:2001106
regulates GO:0003824 GO:2001106
regulates GO:0098772 GO:2001106
is_a GO:0051336 GO:2001106
regulates GO:0003674 GO:2001106
regulates GO:0030234 GO:2001106
regulates GO:0030695 GO:2001106
is_a GO:0051098 GO:2001106
is_a GO:0050790 GO:2001106
regulates GO:0016462 GO:2001106
regulates GO:0017111 GO:2001106
regulates GO:0003924 GO:2001106

2 Synonyms

Name Type
regulation of Rho guanine nucleotide exchange factor synonym
regulation of RhoGEF synonym