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GO:0008150
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biological_process
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A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. |
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GO:0003674
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molecular_function
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A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. |
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GO:0003824
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catalytic activity
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Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
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GO:0016787
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hydrolase activity
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Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
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GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
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GO:0036094
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small molecule binding
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Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. |
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GO:0005488
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binding
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The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. |
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GO:0016817
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hydrolase activity, acting on acid anhydrides
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Catalysis of the hydrolysis of any acid anhydride. |
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GO:0016818
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hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
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Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. |
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GO:0016462
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pyrophosphatase activity
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Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. |
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GO:0017111
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ribonucleoside triphosphate phosphatase activity
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Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. |
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GO:1901363
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heterocyclic compound binding
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Binding to heterocyclic compound. |
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GO:1901265
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nucleoside phosphate binding
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Binding to nucleoside phosphate. |
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GO:0043167
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ion binding
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Binding to an ion, a charged atoms or groups of atoms. |
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GO:0043168
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anion binding
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Binding to an anion, a charged atom or group of atoms with a net negative charge. |
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GO:0050790
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regulation of catalytic activity
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Any process that modulates the activity of an enzyme. |
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GO:0065009
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regulation of molecular function
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Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
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GO:0098772
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molecular function regulator activity
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A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. |
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GO:0000166
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nucleotide binding
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Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
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GO:0035639
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purine ribonucleoside triphosphate binding
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Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. |
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GO:0097367
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carbohydrate derivative binding
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Binding to a carbohydrate derivative. |
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GO:0017076
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purine nucleotide binding
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Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate. |
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GO:0032553
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ribonucleotide binding
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Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. |
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GO:0032555
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purine ribonucleotide binding
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Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. |
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GO:0030234
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enzyme regulator activity
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Binds to and modulates the activity of an enzyme. |
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GO:0003924
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GTPase activity
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Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
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GO:0019001
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guanyl nucleotide binding
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Binding to a guanyl nucleotide, consisting of guanosine esterified with (ortho)phosphate. |
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GO:0032561
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guanyl ribonucleotide binding
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Binding to a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety. |
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GO:0005525
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GTP binding
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Binding to GTP, guanosine triphosphate. |
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GO:0005085
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guanyl-nucleotide exchange factor activity
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Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. |
