WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Anatomy Term :

Definition  Sheath of PDE Name  PDEshL
Primary Identifier  WBbt:0004371 Synonym  lineage name: V5L.papp

1 Children

Definition Name Synonym Primary Identifier
nucleus of pedigree V5L.papp V5L.papp nucleus   WBbt:0002601

1 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Single-cell RNA-Seq cell group 82_1 with unidentified tissue expression pattern. scVI 0.6.0 WBPaper00065841:82_1

3 Expression Patterns

Remark Reporter Gene Primary Identifier Pattern Subcellular Localization
Picture: Fig. 1G, 1H, Fig S1G-L.   Marker30 Expressed in CEPsh glia and in sheath and socket glia of inner and outer labial sensilla, and of the deirid.  
    Expr13568 ztf-6::gfp expression is first observed in late embryogenesis (threefold stage). In early larval stages, the ztf-6::gfp-expressing cells include head hypodermal cells, head muscle cells, neurons, and ectodermal blast cells along the body (all P and all V cells) and in the tail. Starting in the L2 stage, additional neurons in P cell-derived ventral cord motor neurons express ztf-6::gfp. Because of the postdeirid loss phenotype of ztf-6 mutants, we examined the postdeirid lineage in more detail. We observe ztf-6 expression in the V5 cell of freshly hatched L1 animals. Upon division of the V5 cell into a posterior and anterior daughter, we observe expression in both the anterior and posterior daughters of the V5 cell. The descendent of the posterior V5.p daughter, V5.pa (the founder of the postdeirid lineage), and V5.pp also continue to express ztf-6::gfp. Within the V5.pa lineage, expression of ztf-6::gfp is retained in the blast cells that generate the glial cells and the PDE and PVD neurons (v5.paaa, V5.papa, V5.paap, V5.papp). No expression is detected at later stages in this lineage.  
The same pattern of expression was also noted when a genomic fragment spanning nucleotides I-1630 was used to drive the GFP reporter.   Expr943 Both hermaphrodites and males expressed GFP in a group of cells around the pharyngeal corpus, which represented either the sheath or socket cells (PDEso) in the tail, as defined by their openings, position and morphology. GFP expression in these sensory support cells was detected soon after their birth and was maintained into adulthood. A GFP signal was detected in all the ray structure cells of the male tail, but not in the hypodermal tissue. Expression in nine pairs of structure cells began just prior to the ray retraction period, peaked during the retraction and declined upon completion of ray extension.  

0 Life Stages

4 Parents

Definition Name Synonym Primary Identifier
postdeirid sensillum, left. postdeirid sensillum left   WBbt:0006969
posterior lateral ganglion, left side. posterior lateral left ganglion   WBbt:0005464
post-embryonic cell of pedigree V5L.pap V5L.pap   WBbt:0007451
posterior deirid sheath cell. PDE sheath cell   WBbt:0008415