WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  While DMA-1::GFP is dominantly expressed in PVD and FLP, especially by the adult stage, DMA-1::GFP expression in additional head and ventral cord neurons was detected during larval and early adult stages. DMA-1 expression was detected in the PVD cell body shortly after PVD are born (L2 larval stage) before any dendrite outgrowth or branching has occurred. Weaker DMA-1::GFP expression can be seen in ventral cord motorneurons and in the sub-lateral cords.Expression was variable from animal to animal, seen in both commissural and non-commissural motorneurons, and was mostly undetectable by the early adult stage. In the head, expression of DMA-1::GFP was detected during development in additional head neurons besides FLP. Of these neurons, the strongest expression was detected in neurons that run around the nerve ring and extend processes along the sub-lateral cords (likely some combinationof the SIA, SIB, SMB and/or SMD classes of neurons). A number of additional head neurons displayed inconsistent DMA-1::GFP expression from animal to animal. Again, expression in these additional neurons was transient and mostly undetectable by the early adult stage. d, Strong expression DMA-1::GFP was detected in vulva cells during the L3-L4 larval stages. Primary Identifier  Expr9910
Subcellular Localization  Bright DMA-1::GFP localization can be seen in intracellular membrane structures that are likely to be golgi/ER. The plasma membrane is also clearly visible, indicating that DMA-1::GFP is a cell-surface protein.

24 Anatomy Terms

Definition Name Synonym Primary Identifier
female genital. vulva   WBbt:0006748
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring. ventral nerve cord ventral cord WBbt:0005829
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
nerve cord positioned at the lateral flanks of the animal, consists of processes of the neuron classes BDU, CAN, PVD and ALA. lateral nerve cord   WBbt:0006769
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBDL lineage name: ABplppaaaaa WBbt:0004981
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBDR lineage name: ABprppaaaaa WBbt:0004979
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDVL lineage name: ABalppappaa WBbt:0004970
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDVR lineage name: ABarappppaa WBbt:0004969
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDDL lineage name: ABplpapaaaa WBbt:0004972
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMDDR lineage name: ABprpapaaaa WBbt:0004971
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBVL lineage name: ABplpapaapp WBbt:0004978
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIBVR lineage name: ABprpapaapp WBbt:0004977
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIAVL lineage name: ABplpapappa WBbt:0004985
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIAVR lineage name: ABprpapappa WBbt:0004983
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIADL lineage name: ABplpapaapa WBbt:0004989
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally SIADR lineage name: ABprpapaapa WBbt:0004987
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMBVL lineage name: ABalpapappp WBbt:0004974
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMBVR lineage name: ABarappappp WBbt:0004973
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMBDL lineage name: ABalpapapapp WBbt:0004976
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally SMBDR lineage name: ABarappapapp WBbt:0004975
Neuron, lateral process adjacent to excretory canal PVDR lineage name: V5R.paapa WBbt:0004088
Neuron, lateral process adjacent to excretory canal PVDL lineage name: V5L.paapa WBbt:0004090
Neuron, ciliated ending in head, no supporting cells, associated with ILso FLPR lineage name: ABprapaaapad WBbt:0004797
Neuron, ciliated ending in head, no supporting cells, associated with ILso FLPL lineage name: ABplapaaapad WBbt:0004798

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00011345 dma-1 T01G9.3 Caenorhabditis elegans

5 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024