WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Staining embryos with this anti-VAB-7 antibody confirmed that VAB-7 is expressed in posterior muscle and epidermal cells. However, a second phase of VAB-7 expression was discovered in embryonic ventral nerve cord (VNC) neurones, beginning at the 1.5-fold stage. At the threefold stage VAB-7 is expressed in nine neuronal nuclei (seven in the VNC and two nuclei in the head), and in the five most posterior epidermal nuclei, which form the hyp8 to hyp11 cells. VAB-7 is expressed in the seven DB class motoneurones; VAB-7 staining is also seen in two additional head neurones that have not been identified. DB neurones express VAB-7 throughout development. In addition, VAB-7 is expressed continuously in the hypodermal syncitium hyp10, and from the L1 stage in four unidentified neurones in the tail. Finally, at the adult stage, VAB-7 is detected in three VC neurones: VC1, VC2 and VC6. Primary Identifier  Expr1842
Subcellular Localization  nuclei
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18 Anatomy Terms

Definition Name Synonym Primary Identifier
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring. ventral nerve cord ventral cord WBbt:0005829
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum. tail neuron   WBbt:0006759
Contractile cell that makes up muscle tissue. muscle cell   WBbt:0003675
Tail ventral hypodermis, 9th hypodermis cell hyp9   WBbt:0004380
Tail ventral hypodermis hyp10 lineage name: ABplppppppp WBbt:0004378
Tail ventral hypodermis, 8th hypodermis cell hyp8   WBbt:0004381
Tail dorsal hypodermis hyp11 lineage name: Cpappv WBbt:0004377
Ventral cord motor neurons, innervate dorsal muscles DB7 lineage name: ABprppaappp WBbt:0004840
Ventral cord motor neurons, innervate dorsal muscles DB3 lineage name: ABprpaaaapp WBbt:0004844
Ventral cord motor neurons, innervate dorsal muscles DB4 lineage name: ABprpappapp WBbt:0004843
Ventral cord motor neurons, innervate dorsal muscles DB5 lineage name: ABplpapappp WBbt:0004842
Ventral cord motor neurons, innervate dorsal muscles DB6 lineage name: ABplppaappp WBbt:0004841
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles VC1 lineage name: P3.aap WBbt:0004621
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles VC2 lineage name: P4.aap WBbt:0004619
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles VC3 lineage name: P5.aap WBbt:0004618
Ventral cord motor neurons, innervate dorsal muscles DB2 lineage name: ABarappappa WBbt:0004845
Ventral cord motor neurons, innervate dorsal muscles DB1 lineage name: ABplpaaaapp WBbt:0004846

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006873 vab-7 M142.4 Caenorhabditis elegans

9 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  The stage that begins when a C.elegans individual is fully-developed and has reached maturity. adult Ce WBls:0000041
  The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch. L3 larva Ce WBls:0000035
  The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch. L2 larva Ce WBls:0000027
  The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch. L4 larva Ce WBls:0000038
  The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch. L1 larva Ce WBls:0000024
  The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo. fully-elongated embryo Ce WBls:0000021
  The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo. 2-fold embryo Ce WBls:0000019
  The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage. 3-fold embryo Ce WBls:0000020
  The C. elegans life stage spanning 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo. 1.5-fold embryo Ce WBls:0000018