WormMine: ExpressionPattern Expr9047

• Pattern: ARL-8::GFP was widely expressed in many tissues including neurons, muscle, intestine, and coelomocytes in adult worms.
• Primary Identifier: Expr9047
• Remark: Expression of the ARL-8::GFP fusion proteins could rescue the maternal embryonic lethality and coelomocyte phenotypes of arl-8 mutants, suggesting that the GFP fusion proteins are functional and are likely to reflect localization of endogenous ARL-8. No detailed description on expression pattern in other life stages. Picture: Fig 1A, 1B, 1C, Fig S1
• Subcellular Localization: ARL-8::GFP labeled the subsets of intracellular compartments in C. elegans coelomocytes.

5 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Contractile cell that makes up muscle tissue.	muscle cell		WBbt:0003675
A free-floating spherical cell lying in the pseudocoelomic cavity of larvae and adult C. elegans which can endocytose many compounds, possibly for immune surveillance. There are six coelomocytes in adult hermaphrodites, and they display prominent cytoplasmic inclusions and vacuoles.	coelomocyte		WBbt:0005751

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000192	arl-8	Y57G11C.13	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041