WormMine: ExpressionPattern Expr12254

• Pattern: Expression of the Plin-4::GFP-pest reporter peaked in hyp7 and seam cells at the mid- and late-L3 stage and then again at the late-L4 stage. In addition, the majority of animals exhibited a cessation of hyp7 and seam cell Plin-4::GFP-pest expression immediately after L4 ecdysis. In contrast, Plin-4::GFP-pest expression in muscle cells displayed a different transcriptional profile. In the majority of animals, expression of GFP-pest in muscles peaked at L3 ecdysis, gradually diminished throughout the remainder of the L4 stage, and increased again at the young adult stage. These results suggest that, while lin-4 is dynamically expressed once each larval stage, its promoter activity may be differentially regulated in distinct tissues.
• Primary Identifier: Expr12254

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Contractile cell that makes up muscle tissue.	muscle cell		WBbt:0003675
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
entire syncytium of hyp7	hyp7 syncytium	hyp7	WBbt:0005734

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002993	lin-4	F59G1.6	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038