WormMine: ExpressionPattern Expr2880

• Pattern: Relatively strong expression in ganglia in the head and tail and in the anterior pharynx. GFP was not seen in ASI, ASJ, ADF or ASG (0 of 86 animals). Fluorescence in the anterior ganglion, where XXX is found, is at least an order of magnitude less than in the bright cells of the ganglia posterior to the nerve ring. The weakness of fluorescence has precluded identification of specific cells, but sometimes weak fluorescence was seen in the ventral, anterior part of the ganglion, where XXX resides (seven out of 53 animals). A small number of animals show weak expression in the hypodermis, muscles, intestine and distal tip cells.
• Primary Identifier: Expr2880
• Subcellular Localization: DAF-5::GFP from the rescuing construct mostly localizes to nuclei, which is consistent with the idea that DAF-5 is a transcription factor and functions in the nucleus. The intensity of fluorescence and nuclear localization of DAF-5::GFP from the rescuing construct was examined in wild-type and in TGF pathway mutants, including dauers, and no obvious differences was seen.

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	anterior distal tip cell	gon herm dtc A	WBbt:0004520
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	posterior distal tip cell	gon herm dtc P	WBbt:0004506
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum.	tail neuron		WBbt:0006759
Contractile cell that makes up muscle tissue.	muscle cell		WBbt:0003675
ganglion in the head.	head ganglion		WBbt:0005135
Embryonic head hypodermal cell	XXXR	lineage name: ABarpappaa	WBbt:0004579
Embryonic head hypodermal cell	XXXL	lineage name: ABplaaapaa	WBbt:0004581

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000901	daf-5	W01G7.1	Caenorhabditis elegans

0 Life Stages