WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  tbc-8 is exclusively expressed in neurons including the head and tail neurons as well as neurons in the ventral nerve cord (VNC). Primary Identifier  Expr10033
Subcellular Localization  Fluorescently labeled TBC-8 showed a cytosolic localization with some punctate membrane staining. Partial localization of TBC-8 was observed with medial (mannosidase II) and trans-Golgi (APT-9) markers and an almost complete co-localization with the early endosomal marker RAB-5. However, we could not observe any localization of TBC-8 to RAB-7-positive late endosomes. This suggests that TBC-8 acts at the Golgi-endosomal interface.
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4 Anatomy Terms

Definition Name Synonym Primary Identifier
neuron with cell body associated with the ventral nerve cord. ventral cord neuron ventral cord motoneuron WBbt:0005300
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum. tail neuron   WBbt:0006759
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses. neuron neurone WBbt:0003679

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00008018 tbc-8 C38H2.1 Caenorhabditis elegans

0 Life Stages