WormMine: ExpressionPattern Expr11333

• Pattern: In L1 larval animal expressing the mnr-1::GFP reporter weak expression is seen in some unidentified neurons in the head and tail region as well as possibly some lateral hypodermal cells and the anterior pharyngeal bulb. At the L3 larval stage clear GFP expression was seen in the ventral, dorsal, and lateral hypodermal ridges. Some neuronal staining may persist at this stage.
• Primary Identifier: Expr11333
• Subcellular Localization: The mCherry-tagged MNR-1 was distributed evenly within the hypodermal ridges in a punctate pattern that appeared to be independent of SAX-7 and DMA-1. Interestingly, the tagged protein also labeled vesicles within the coelomocytes, a set of scavenger cells that are known to take up and degrade secreted proteins from the extracellular space. Thus, the mCherry::MNR-1 fusion was extracellular and either diffusible under the experimental conditions or cleaved from the membrane.

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum.	tail neuron		WBbt:0006759

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00012184	mnr-1	W01F3.1	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023