1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004130 | ketn-1 | F54E2.3 | Caenorhabditis elegans |
| Primary Identifier | Expr7982 | Remark | Picture: Figure 3. |
| Subcellular Localization | Authors reexamined intracellular localization of Ce-kettin by double or triple staining with other cytoskeletal markers and found that it localized to a portion, not the entire length, of the I-bands. Triple staining of body wall muscle for actin (thin filaments), Ce-kettin (MH44), and myosin heavy chain (thick filaments) confirmed that Ce-kettin is associated with the thin filaments. However, Ce-kettin localized to a ladder-like pattern and its localization was limited to a narrow region in the middle of the bands of actin. Triple staining for actin, Ce-kettin, and vinculin (dense bodies) showed that Ce-kettin has some overlap with vinculin, but the center of the dense bodies was devoid of Ce-kettin. In addition, comparison with the location of tropomyosin showed that tropomyosin localized to the outer region on the thin filaments with minimal overlap with Ce-kettin. These results indicate that Ce-kettin is associated with a portion of the thin filaments near the dense bodies. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004130 | ketn-1 | F54E2.3 | Caenorhabditis elegans |
