WormMine: ExpressionPattern Expr12869

• Pattern: qui-1::GFP was visible in the processes of the nerve ring and in several neurons of the lateral and ventral ganglia, including the avoidance sensory neurons ASH and ADL. GFP expression was not detected in ASK sensory neurons. Four additional neurons in the retrovesicular ganglion and two neurons in the lumbar ganglion, PVQ and the sensory neuron PHB, also express GFP. This expression pattern partially overlaps but is not completely coincident with that obtained with a much shorter construct in which GFP was fused to the second exon, and the construct was thus missing part of exon 2 and the last 17 introns and exons of the gene (not shown). Expression from this shorter construct included neither ASH nor PHB, indicating that important regulatory elements are present within the coding region of qui-1.
• Primary Identifier: Expr12869
• Subcellular Localization: In the ASH sensory neurons, the reporter protein uniformly stained the cell body, nucleus, dendrite and axon. The staining was too faint to unambiguously determine whether QUI-1::GFP localized also in the cilia. In most of the other neurons, expression of GFP was lower in all cellular compartments and apparently absent from the nucleus.

13 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASHL	lineage name: ABplpaappaa	WBbt:0003890
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASHR	lineage name: ABprpaappaa	WBbt:0003889
Interneuron, projects along ventral cord to ring	PVQL	lineage name: ABplapppaaa	WBbt:0004076
Interneuron, projects along ventral cord to ring	PVQR	lineage name: ABprapppaaa	WBbt:0004074
Amphid neuron, prob. chemosensory	ADLL	lineage name: ABalppppaad	WBbt:0003997
Amphid neuron, prob. chemosensory	ADLR	lineage name: ABpraaapaad	WBbt:0003995
Phasmid neurons, probably chemosensory	PHBL	lineage name: ABplapppappp	WBbt:0004364
Phasmid neuron, probably chemosensory	PHBR	lineage name: ABprapppappp	WBbt:0005659
Ganglion that lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore. It is open and continuous with the region containing the motoneurons of the ventral cord. In the early L1 this ganglion holds 12 neuron cell bodies plus one neuroblast (Sulston and Horvitz, 1977; White et al., 1986). In the adult animal, the ganglion holds 20 neuron cell bodies.	retrovesicular ganglion		WBbt:0005656
The left and right lumbar ganglia lie behind the pre-anal ganglion in the tail, in lateral positions. Each contains 12 neuron cell bodies that send most of their neuronal processes into the ventral nerve cord via lumbar commissures and the pre-anal ganglion. There is no local neuropil in these ganglia in the hermaphrodite, instead they form most synapses in the pre-anal ganglion. Most lumbar neurons have sensory functions. In the adult male tail, these two ganglia gain many additional neurons and have some local neuropil. The lumbar neurons lie in close association with the lateral hypodermis, and most are posterior to the anus.	lumbar ganglion	lumbar lateral ganglia	WBbt:0005830
The left and right lateral ganglia lie beside the nerve ring in the head. They each contain about (30) neuron cell bodies and send their neuronal processes into the ring at its posterior margin either laterally or ventrally via the amphid commissures and ventral ganglion, but form no local neuropil separate from the nerve ring. The lateral ganglia are in close contact with the lateral hypodermal cords.	lateral ganglion	lateral ganglia	WBbt:0005105
ganglion lies beside the nerve ring in the head, just anterior of the retrovesicular ganglion. It contains about 20 interneuron and motorneuron cell bodies that all send their neuronal processes into the ring. The cell bodies are divided into two groups by the intrusion of the excretory duct and canal. The cells are bounded by a basal lamina which physically separates them from the lateral ganglion even though they are adjacent to one another.	ventral ganglion	ventral ganglia	WBbt:0005298

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004265	qui-1	Y45F10B.10	Caenorhabditis elegans

0 Life Stages