WormMine: ExpressionPattern Expr13724

• Pattern: Using a fosmid-based reporter transgene, the previously reported expression of unc-6 in the AVG neuron up to early larval stages was corroborated. However, the expression in the AVG neurons of hermaphrodites begins to fade during the L3 stage, before sexual maturation, and is undetectable by the young adult stage. In contrast, expression is maintained in males during sexual maturation in the L4 stage into the young adult stage. Non-dimorphic unc-6 expression is observed in other neuron classes, some of which maintain unc-6 expression into adulthood (e.g., RIF neurons), whereas others do not (e.g., AVA neurons). Consistent with the expression pattern of the fosmid reporter, we observed robust unc-6 mRNA signals (single molecule FISH) in both sexes of first larval stage animals and strongly sexually dimorphic levels during sexual maturation in the L4 stage.
• Primary Identifier: Expr13724

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha	AVAL	lineage name: ABalppaaapa	WBbt:0003870
Ventral cord interneuron, synapses onto VA, DA, and AS motor neurons; formerly called alpha	AVAR	lineage name: ABalaappapa	WBbt:0003869
Ring interneuron	RIFR	lineage name: ABprppapaaap	WBbt:0003934
Ring interneuron	RIFL	lineage name: ABplppapaaap	WBbt:0003936
Gonochoristic organism that can produce male gametes.	male	male organism	WBbt:0007850
Multi-cellular organism that can produce both male and female gametes.	hermaphrodite	hermaphroditic organism	WBbt:0007849

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006746	unc-6	F41C6.1	Caenorhabditis elegans

0 Life Stages