WormMine: ExpressionPattern Expr11460

• Pattern: A fosmid reporter construct, which contains more than 30 kb surrounding the ttx-3 locus and which rescues the AIY differentiation defect of ttx-3 mutant animals, mirrors the expression of a smaller, locus-restricted reporter construct described earlier (Altun-Gultekin et al., 2001) in the AIY, the AIA, the AIN and a previously uncharacterized neuronal pair in the pharyngeal nervous system. Based on position, morphology and colabeling with the NSM marker mgl-1::mCherry, the authors identified the pharyngeal neurons that express ttx-3 as the NSM neuron pair. There are also notable differences in the expression pattern of the fosmid reporter and the smaller reporters. First, expression in the AIN neurons is maintained throughout development with the fosmid reporter, whereas it is restricted to embryos with smaller reporters (Bertrand and Hobert, 2009). Second, the expression in amphid sensory neurons is markedly different. In larval and adult animals, the fosmid reporter is expressed in the ASK neuron class, whereas the smaller reporters are expressed in the ADL and ASI sensory neurons.
• Primary Identifier: Expr11460

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Amphid interneuron	AIYL	lineage name: ABplpapaaap	WBbt:0003963
Amphid interneuron	AIYR	lineage name: ABprpapaaap	WBbt:0003961
Pharyngeal neurosecretory motorneuron, contain serotonin	NSMR	lineage name: ABaraapppaav	WBbt:0004446
Pharyngeal neurosecretory motorneuron, contain serotonin	NSML	lineage name: ABaraapapaav	WBbt:0004457
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASKL	lineage name: ABalpppapppa	WBbt:0003884
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASKR	lineage name: ABpraaaapppa	WBbt:0003883
Amphid interneuron	AIAL	lineage name: ABplppaappa	WBbt:0003989
Amphid interneuron	AIAR	lineage name: ABprppaappa	WBbt:0003987
Ring interneuron	AINR	lineage name: ABalaapaaar	WBbt:0003965
Ring interneuron	AINL	lineage name: ABalaaaalal	WBbt:0003967

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006654	ttx-3	C40H5.5	Caenorhabditis elegans

0 Life Stages