WormMine: ExpressionPattern Expr2276

• Pattern: Neuronal expression. In the L1 stage cog-1::gfp is expressed in amphid neurons ADL(L/R), ASE(L/R), and ASJ(L/R). One additional pair of head neurons expresses cog-1::gfp in the L1. This pair is located between the excretory cell and the excretory pore, and is probably either AIA(L/R), SMBD(L/R), SIAD(L/R), or SIAV(L/R). In the tail, phasmid neurons PHB(L/R) express cog-1::gfp. The expression in amphid and phasmid neurons persists to the adult. Additional unidentified cells in the preanal ganglion express cog-1::gfp in late larvae and adults. Other cells in the tail region. The sphincter muscle (mu_sph) and phasmid sheath cells (PHshL, PHshR) express cog-1::gfp in all stages examined. Uterine expression. In the hermaphrodite gonad, cog-1::gfp is expressed exclusively in the dorsal uterine lineage. During the L3 stage, GFP is in the central four great-granddaughters of DU cells (DE4/DE5; DE, dorsal eight). The expression apparently persists in DE4/DE5 descendants, du, uv2, and uv3, until the adult stage, DE2 and DE7 lineages in the dorsal uterus also express cog-1::gfp starting from the early L4 stage. In the late L4, cog-1::gfp in this region is observed exclusively in sujc cells. Each core is surrounded by the spermathecaluterine valve and appears to form a plug which blocks the uterine lumen from the spermathecal lumen. None of the cog-1::gfp fusions, including the rescuing construct, was ever observed to express in any ventral uterine cells, including the anchor cell. Thus, the function of cog-1 in the connection is believed to be a consequence of abnormal gene regulation in the vulva, although a function in the dorsal uterine cells have not been ruled out. Vulval expression. In the vulva, cog-1::gfp is expressed from early L4 to the adult. Cells that express are vulC [P5.ppa(l/r), P7.pap(l/r)], vulD (P5.ppp, P7.paa), vulE(P6.pppl, P6.pppr, P6.paal, P6.paar), and vulF (P6.ppal, P6.ppar, P6.papl, P6.papr). The expression is considerably brighter in vulC and vulD than in vulE and vulF. Occasionally, expression in vulB and vulA was observed. Male expression. The expression of cog-1::gfp in the male was scored mostly in animals containing an extrachromosomal array containing the SmaI insertion. cog-1::gfp is expressed during proctodeal development. eL.aav and eR.aav express cog-1. In addition, proctodeal cells B.pap and B.pppa express cog-1::gfp. Additional expressing cells observed in occasional males include: rep, and P11.pp progeny. No gonadal cells in the male, including the linker cell, expressed cog-1::gfp in any stage of development.
• Primary Identifier: Expr2276

34 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
a saddle-shaped muscle cell that encircles the intestinal-rectal valve	anal sphincter muscle	lineage name: ABprpppppap	WBbt:0005798
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASEL	lineage name: ABalppppppaa	WBbt:0003904
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASER	lineage name: ABpraaapppaa	WBbt:0003903
Amphid neuron, prob. chemosensory	ADLL	lineage name: ABalppppaad	WBbt:0003997
Amphid neuron, prob. chemosensory	ADLR	lineage name: ABpraaapaad	WBbt:0003995
Phasmid neurons, probably chemosensory	PHBL	lineage name: ABplapppappp	WBbt:0004364
Phasmid neuron, probably chemosensory	PHBR	lineage name: ABprapppappp	WBbt:0005659
adult vulval toroid cell, F, formed by fusion of precursors of lineage names P6.papl, P6.papr, P6.ppal and P6.ppar.	vulF		WBbt:0006768
adult vulval toroid cell, E, formed by fusion of precursors of lineage names P6.paal, P6.paar, P6.pppl and P6.pppr.	vulE		WBbt:0006767
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIAVL	lineage name: ABplpapappa	WBbt:0004985
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIAVR	lineage name: ABprpapappa	WBbt:0004983
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIADL	lineage name: ABplpapaapa	WBbt:0004989
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIADR	lineage name: ABprpapaapa	WBbt:0004987
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMBDL	lineage name: ABalpapapapp	WBbt:0004976
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMBDR	lineage name: ABarappapapp	WBbt:0004975
adult vulval toroid cell, C, formed by fusion of precursors of lineage names P5.ppal, P5.ppar, P7.papl and P7.papr.	vulC		WBbt:0006765
adult vulval toroid cell, D, formed by fusion of precursors of lineage names P5.ppp and P7.paa.	vulD		WBbt:0006766
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASJR	lineage name: ABpraaappppa	WBbt:0003885
one member of Amphid neurons, single ciliated endings, probably chemo-sensory; project into ring via commissure from ventral ganglion, make diverse synaptic connections in ring neuropil	ASJL	lineage name: ABalpppppppa	WBbt:0003886
Amphid interneuron	AIAL	lineage name: ABplppaappa	WBbt:0003989
Amphid interneuron	AIAR	lineage name: ABprppaappa	WBbt:0003987
uterine-vulva cell, distal (of three ut cells) to the vulva.	uv3		WBbt:0006793
uterine-vulval cell, medial position of three ut cells.	uv2		WBbt:0006792
Phasmid sheath	PHshL	lineage name: ABplpppapaa	WBbt:0004116
Phasmid sheath	PHshR	lineage name: ABprpppapaa	WBbt:0004114
cell forming dorsal epithelium in central region of the uterus; formed by fusion of four cells.	dorsal uterine cell	du cell	WBbt:0006782
Hypodermis associated with hook sensillum of male, contains nucleus P11.ppaa	P11.ppaa	lineage name: P11.ppaa	WBbt:0004374
Hypodermis associated with hook sensillum of male, contains nucleus P11.ppp	P11.ppp	lineage name: P11.ppp	WBbt:0004372
Hypodermis associated with hook sensillum of male, contains nucleus P11.ppap	P11.ppap	lineage name: P11.ppap	WBbt:0004373
Cell of male proctodeum, post-embryonic pedigree B.pap.	B.pap	lineage name: B.pap	WBbt:0004811

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000584	cog-1	R03C1.3	Caenorhabditis elegans

0 Life Stages