WormMine: ExpressionPattern Expr2708

• Pattern: A dop-1::gfp reporter gene fusion has a more restricted expression pattern in the nervous system in larval and adult animals. Within the head ganglia, dop-1prom1::gfp is consistently expressed only in the RIS interneuron class. Only weak and inconsistent expression can be observed in other unidentified head neurons. Consistent and strong expression can be observed in the excretory gland cells and head muscles as well as in several labial and amphid sensory neuron support cells (sheath/socket cells). In the midbody and tail region, reporter gene expression is evident in the AVM and ALM touch sensory neurons, in the ALN and PLN neuron classes and in the PVQ interneurons, which extend axons along the left and right ventral nerve cord, respectively. Reporter gene fusions that contain more genomic sequence (dop-1prom2::gfp and dop-1trans::gfp;) show expression in similar sets of cells. In addition, dop-1prom2::gfp expression is observed in additional sets of unidentified head neurons.
• Primary Identifier: Expr2708
• Subcellular Localization: A dop-1trans::gfp reporter protein, which contains dop-1 coding sequences, is localized to the plasma membrane and has a punctate appearance along axons and muscle arms.

15 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
An interfacial epithelial cell which forms a distal cap on a sheath cell to bind the sheath of a sensillum to the neighboring hypodermis, via adherens junctions. There is often a narrow opening through the socket from the exterior into the sheath channel, allowing ciliated dendrites to be exposed to the external environment. The socket cell functions similarly to a glial cell.	socket cell		WBbt:0005750
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
body wall muscle in the head, including first eight cells of each muscle quadrants which are innervated by nerve ring neurons.	head muscle	head body wall muscle	WBbt:0006761
gland cell of the secretory-excretory system, sends processes to ring, opens into excretory duct.	excretory gland cell	exc gl	WBbt:0005776
Interneuron, associated with PLM	PLNL	lineage name: TL.pppap	WBbt:0004102
Interneuron, associated with PLM	PLNR	lineage name: TR.pppap	WBbt:0004098
a structural (glial) cell which forms an specialized environment surrounding the sensory ending(s) of one or more neurons; sometimes accompanied by a more distal socket cell. In early development of the sensory nerves and of the nerve ring some sheath cells (cephalics and labials) may also provide a substrate for axon guidance	neuronal sheath cell	pocket cell	WBbt:0005811
Interneuron, projects along ventral cord to ring	PVQL	lineage name: ABplapppaaa	WBbt:0004076
Interneuron, projects along ventral cord to ring	PVQR	lineage name: ABprapppaaa	WBbt:0004074
Neuron class of one sensory neuron, anterior ventral microtubule cell, touch receptor.	AVM	lineage name: QR.paa	WBbt:0003832
Anterior lateral microtubule cell, touch receptor	ALML	lineage name: ABarppaappa	WBbt:0003954
Anterior lateral microtubule cell, touch receptor	ALMR	lineage name: ABarpppappa	WBbt:0003953
Neuron class of one ring interneuron.	RIS	lineage name: ABprpappapa	WBbt:0005045
Neuron associated with ALM	ALNL	lineage name: ABplapappppap	WBbt:0003939
Neuron associated with ALM	ALNR	lineage name: ABprapappppap	WBbt:0003937

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001052	dop-1	F15A8.5	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024