WormMine: ExpressionPattern Expr14246

• Pattern: We dissected and isolated pharynxes from two nlg-1 transcriptional reporter strains and established that there is no nlg-1 expression in the pharynx or in its associated microcircuit. We found no co-expression of neuroligin in ADF and no expression in major sensory neuron classes, using specific markers for the following neurons: ASJ, AWB, AWC and ASE neurons. However, although neuroligin is not expressed in NSM we found expression in HSN neurons in the vulva area. Finally, to further investigate expression in a subset of sensory neurons we tried to identify neuroligin expression in the DiI labelled amphid neurons: ADL, ASH, ASI, ASJ, ASK, AWB: Again we found no neuroligin expression. However, nlg-1 is expressed in a subset of eat-4 glutamatergic neuron classes. In addition, neuroligin expression was localized specifically in a subset of dopaminergic sensory neurons, ADEs, which also are involved in food-dependent behaviours (Hills, Brockie et al. 2004), as well as in the bilateral interneurons AIY, that function to extend food-seeking periods (Shtonda and Avery 2006). Finally, by positional identification of cell bodies we found expression of nlg-1 in the sensory neurons ALA and URX, as well as the interneuron AVJ.
• Primary Identifier: Expr14246

11 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Ring interneuron	URXL	lineage name: ABplaaaaappp	WBbt:0004928
Ring interneuron	URXR	lineage name: ABarpapaappp	WBbt:0004926
Amphid interneuron	AIYL	lineage name: ABplpapaaap	WBbt:0003963
Amphid interneuron	AIYR	lineage name: ABprpapaaap	WBbt:0003961
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNL	lineage name: ABplapppappa	WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNR	lineage name: ABprapppappa	WBbt:0004757
Neuron class of one neuron, sends processes laterally and along dorsal cord.	ALA	lineage name: ABalapppaaa	WBbt:0003955
Anterior deirid, sensory neuron, dopaminergic	ADEL	lineage name: ABplapaaaapa	WBbt:0004009
Anterior deirid, sensory neuron, dopaminergic	ADER	lineage name: ABprapaaaapa	WBbt:0004007
Neuron, synapses like AVHL/R	AVJR	lineage name: ABalapppppa	WBbt:0003846
Neuron, synapses like AVHL/R	AVJL	lineage name: ABalapapppa	WBbt:0003847

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006412	nlg-1	C40C9.5	Caenorhabditis elegans

0 Life Stages