WormMine: ExpressionPattern Expr2929

• Pattern: plx-2 expression occurs predominantly in the nervous system from embryonic to adult stages. The onset of plx-2 reporter expression coincides with the normal timing of outgrowth or migration (e.g., CAN) of these neurons. Several nonneuronal tissues also express evIs136[plx-2::gfp] and evIs168[plx-2(+)::GFP] including gonadal sheath, vulva precursors, and excretory canal. Of most relevance, expression of both the transcriptional and translational reporters occurs throughout a number of stages of sensory ray morphogenesis in the male tail. Expression of the plx-2 translational reporter evIs168[plx-2::GFP] is observed during ray morphogenesis at the Rn stage in the early L3 larva in R1, 3, 5, and 7. This reporter continues to express faintly in the Rn.a descendents that form rays 1, 3, 5, and 7 of late L3 larvae, which coincides with the period during which lineally related Rn.a descendants sort from neighboring Rn.a descendants to form distinct rays. However, in mid-L4 larvae, expression appears restricted to the ray structural cell (Rnst) for rays 3, 5, 6, and 7, and this expression continues into the late-L4 larval stage. Ray 1 expression of both reporters is undetectable in late L4 larvae.
• Primary Identifier: Expr2929
• Reporter Gene: Transgenic animals carrying an integrated array of the transcriptional reporter evIs136[plx-2::gfp] or the translational reporter evIs168[plx-2::GFP] were analyzed. The transcriptional and translational plx-2 GFP reporters are expressed in the same cells including several that undergo guided migrations during development.

11 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
H-shaped cell associated with the excretory system, largest cell in C. elegans.	excretory cell	excretory canal cell	WBbt:0005812
five pairs of thin gonadal sheath cells form a single layer covering the germ line component of each arm, each pair occupying a stereotyped position along the gonad proximal-distal axis.	gonadal sheath cell		WBbt:0005828
cell that has the potential to form structural part of a vulva.	vulval precursor cell	VPC	WBbt:0007809
Post-embryonic cell of pedigree V6R.pppppapp, male sensory rays, structural cell.	R6stR	lineage name: V6R.pppppapp	WBbt:0004008
Post-embryonic cell of pedigree TL.apappapp, male sensory rays, structural cell.	R7stL	lineage name: TL.apappapp	WBbt:0003998
Male sensory rays, structural cell	R7stR	lineage name: TR.apappapp	WBbt:0003996
Post-embryonic cell of pedigree V6L.ppppaapp, male sensory rays, structural cell.	R5stL	lineage name: V6L.ppppaapp	WBbt:0004020
Post-embryonic cell of pedigree V6R.ppppaapp, male sensory rays, structural cell.	R5stR	lineage name: V6R.ppppaapp	WBbt:0004019
Post-embryonic cell of pedigree V6L.pppppapp, male sensory rays, structural cell.	R6stL	lineage name: V6L.pppppapp	WBbt:0004010
Post-embryonic cell of pedigree V6L.papppapp, male sensory rays, structural cell.	R3stL	lineage name: V6L.papppapp	WBbt:0004032
Post-embryonic cell of pedigree V6R.papppapp, male sensory rays, structural cell.	R3stR	lineage name: V6R.papppapp	WBbt:0004031

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004048	plx-2	K04B12.1	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003