WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  While the expression of VGLU-2::GFP is similar during larval and adult stages inwell fed animals, the expression and localization pattern of VGLU-2::GFP is alteredsubstantially in dauer stage animals. Expression from the AIA neurons disappears and in the epidermis, the localization of VGLU-2::GFP appears much weaker and more diffuse. Upon recovery from the dauer stage, VGLU-2::GFP expression andlocalization resumes to the state observed in animals that have not gone through the dauer stage. Starvation alone does not affect VGLU-2::GFP expression and localization. Primary Identifier  Expr14917
Subcellular Localization  vglu-2::gfp is exclusively expressed in a single interneuron class, AIA, where it localizes to vesicular structures in the soma, but not along the axon. In syncytial epidermis and in uterine tissue vglu-2::gfp most prominently localizes to early endosomes, and to a lesser degree apical clathrin-coated pits, TGN, and late endosomes.

1 Anatomy Terms

Definition Name Synonym Primary Identifier
Epidermal layer. hypodermis epidermis WBbt:0005733

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00010755 vglu-2 K10G9.1 Caenorhabditis elegans

1 Life Stages

Remark Definition Other Name Public Name Primary Identifier
  A third stage larva specialized for dispersal and long term survival. dauer larva Ce WBls:0000032