WormMine: AnatomyTerm WBbt:0004066

• Definition: Interneuron, posterior ventral cord, few synapses.
• Name: PVWL
• Primary Identifier: WBbt:0004066
• Synonym: lineage name: TL.ppa

1 Children

Definition	Name	Synonym	Primary Identifier
nucleus of pedigree TL.ppa	TL.ppa nucleus		WBbt:0002637

1 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Single-cell RNA-Seq cell group 80_0 expressed in neuron.	scVI 0.6.0	WBPaper00065841:80_0

45 Expression Patterns

• Primary Identifier: Expr15558

• Primary Identifier: Expr15571

• Primary Identifier: Expr15572

• Primary Identifier: Expr15573

• Primary Identifier: Expr15579

• Primary Identifier: Expr2937
• Pattern: Both ahr-1:GFP reporters are expressed during embryonic and larval development. Expression is first detected in two cells 260 min after the first cleavage. By midembryogenesis (pre-comma stage), 14 cells express the pJ360 ahr-1:GFP fusion gene. At the 2-fold stage of embryogenesis, two cells express ahr-1:GFP in the tail, and the remaining fluorescing cells are in the forming head. During the first larval stage. ahr-1:GFP is expressed in 28 neurons, several blast cells, and two phasmid socket cells. The neurons that express ahr-1:GFP include ALNR/ALNL, AQR/PQR, AVM/PVM, BDUR/BDUL, PLMR/PLML, PLNR/PLNL, PHCL/PHCR, PVWL/PVWR, RMEL/RMER, SDQR/SDQL, and URXR/URXL. The T.pa, T.ppa, and T.ppp blast cells in the tail express ahr-1:GFP, as do all of their descendents, including the PHso1 and PHso2 phasmid socket cells. ahr-1:GFP is also expressed in the MI and I3 neurons in the pharynx and the G2 and W blast cells. Four additional cells in the head express ahr-1:GFP, tentatively identified as the ASK and RIP neurons.
• Subcellular Localization: The pJ360 construct includes the entire ahr-1 genomic sequence, and transgenic animals express this fusion protein in a subset of neuronal nuclei. The pHT102 transgene lacks most of the ahr-1 coding sequence and labels axons as well as nuclei.

• Primary Identifier: Expr15586

• Primary Identifier: Expr15651

• Primary Identifier: Expr15652

• Primary Identifier: Expr15589

• Primary Identifier: Expr15591

• Primary Identifier: Expr15598

• Primary Identifier: Expr15604

• Primary Identifier: Expr14590
• Pattern: Embryonic expression of exc-7 was first observed at the bean stage. By reverse lineaging with use of SIMI-Biocell software, we confirm the identity of one of the expressing cells at this stage as the excretory canal cell. In L1 animals, broad expression in the head, ventral nerve cord (VNC), and tail was observed. In young adults, expression is notably observed in vulva cells. In the nervous system specifically, expression is observed in many neurons throughout the body, but unlike Drosophila Elav, exc-7::gfp it is not panneuronally expressed. We confirmed previously reported expression in cholinergic VNC MNs, but absence of GABAergic VNC MNs, consistent with previous reports (Fujita et al., 1999; Loria et al., 2003) and consistent with exc-7 functioning in cholinergic, but not GABAergic neurons to control alternative splicing (Norris et al., 2014). exc-7::gfp is also expressed in some non-neuronal cell types, including muscle and hypodermis, but not in the gut. A previous report showed that exc-7 is only transiently and weakly expressed in the excretory cell, which, based on exc-7's excretory mutant phenotype, has puzzled researchers (Fujita et al., 2003). We find that the gfp tagged exc-7 locus is strongly and continuously expressed in the excretory canal cell.

• Primary Identifier: Expr15608

• Primary Identifier: Expr15611

• Primary Identifier: Expr10592
• Pattern: Transcriptional reporters were expressed in neurons and body wall muscle and were similarly expressed in both males and hermaphrodites. Colocalization with other reporters and anatomical criteria enabled identification of the expressing neurons as the cili­ated sensory neurons OLL, PHA and PQR, the nonciliated sensory neurons URY and URX, the touch receptor neurons ALM, PLM, AVM and PVM, the interneurons in the retro-vesicular ganglion RIF and AVF, the command interneurons AVD and PVC, the ring motor neurons RMED and RMEV, and two other neurons tentatively identified as either PVQ or PVW and DB2. No expression was observed in amphid or male-­specific neurons.

• Primary Identifier: Expr8675
• Remark: Picture: N.A.
• Pattern: Expression in the alimentary canal: Strong and consistent expression in pm5, MC. Weak or rare expression in pharyngeal epithelium, pm1, pm2, pm3, pm4 pm6, pm7, pm8, g1, g2, rectal gland cells. Expression in the nervous system: ADE, AIY, ALM, ALN, AVA, AVK, AVM, BDU, CAN, DAn, DVA, DVB, DVC, FLP, HSN, LUA, PLM, PLN, PVC, PVM, PVP, PVQ, PVT, PVW, RID, RIS, SDQ, URB, MC. Expression in the reproductive system: In adult stage, expressed in HSN. Faint hypodermal expression of inx-7 is seen around two-fold stage and becomes stronger by threefold stage.

• Primary Identifier: Expr15564

• Primary Identifier: Expr8694
• Remark: Picture: Fig 3.
• Pattern: Expression in the alimentary canal: Strong and consistent expression in M5, I1, I3, I6, NSM. Weak or rare expression in posterior arcades. Expression in the nervous system: Phsh, ADA, ADE, ADL, AIN, AIY, ALM, AUA, AVA, AVD, AVH, AVJ, AVK, AVM, AWB, BDU, CAN, CEP, DAn, DBn, DDn, DVB, DVC, FLP, HSN, IL1, IL2, LUA, OLL, PDA, PDB, PDE, PHA, PHB, PHC, PLM, PLN, PVC, PVD, PVM, PVN, PVP, PVQ, PVR, PVT, PVW, RIB, RIC, RIF, RIP, RIS, RME, SDQ, SIA (early larva), SIB (early larva), SMB (early larva), SMD (early larva), URA, URB, VAn, VBn, VCn, VDn, M5, I1, I6, NSM. Expression in the reproductive system: In adult stage, expressed in vulval muscle, uterine muscle, HSN, VCn. In developing larva stage, expressed in HSN, VCn, and anchor cell.

• Primary Identifier: Expr1056
• Remark: Reporter gene fusion type not specified. late embryo(author) = fully-elongated embryo (wjc)
• Pattern: GFP expression in the anterior was observed in the sensory neurons AFDL/R, in the interneurons BDUL/R, and in the asymmetrical interneuron ALA. The expression pattern of the GFP constructs was continuous from the late embryonic through all larval stages and maintained in adults. Both constructs show the same expression pattern. Larval and adult expression of CEH-14 protein in AFDL/R and BDUL/R was confirmed by immunolocalization using the CEH-14-specific antiserum. One additional cell expressing CEH-14 was observed in the head, at a location consistent with that for ALA. The staining was always nuclear. In the tail region, ceh-14 is expressed in PVT, PVQL/R, DVC, PVNL/R, PVWL/R, PVR, PHCL/R, PHAL/R, and PHBL/R.
• Subcellular Localization: Always expressed in nuclei.

• Primary Identifier: Expr15648

• Primary Identifier: Expr13161

• Primary Identifier: Expr15657

• Primary Identifier: Expr13162

• Primary Identifier: Expr10986
• Pattern: ceh-14 expression starts around the 280 min stage mainly in the anterior part of the embryo. In later stages (comma stage), the expression is seen in more cells in the head, but also in some cells in the tail. Judged by position and shape, most of them are neuronal precursors, although we have not precisely identified them. From larval to adult stages, neuronal expression is observed in the ALA interneuron and a pair of sensory neurons, AFDL/R, in the head, and in the BDUL/R interneurons in the anterior body (see also Cassata et al., 2000a). In the tail, we see expression in the sensory- and interneurons PHAL/R, PHBL/R, PHCL/R, DVC, PVCL/R, PVNL/R, PVQL/R, PVT, PVWL/R and PVR. The neuronal expression in the head and tail is confirmed by an anti-CEH-14 rabbit antiserum. We also note expression in the six touch neurons ALML/R, AVM, PVM and PLML/R, although it is seen only in strains with integrated reporter constructs. In addition to the neuronal expression, ceh-14 expression is also seen in the hypodermis and spermatheca as previously described (Kagoshima et al., 2000).

• Primary Identifier: Expr8774
• Remark: Picture: Fig. 4.
• Pattern: GFP fluorescence was detected in 20 neurons. In the head, DKF-2BGFP accumulated in amphid sensory neurons (ASE, AFD, ASG, AWC, and AWA), integrative interneurons (AIM, RIC, AIY, AVF, AVJ, AVK, ADA, and RMG), neurons involved in social feeding and O2 sensing (AUA, URX, PQR, AQR, and BAG), and the neurosecretory motor neuron NSM. DKF-2BGFP also accumulated in PVQ, PVR, and PVW interneurons in the tail. DKF-2BGFP was observed in late embryos, L1 to L4 larvae, and adult animals.

• Primary Identifier: Expr3021
• Pattern: Expressed in AIM, ASG, AVA, AVG, AVL, CEP, PVD, PVW, RIC/AIZ, RIV, SMD, URA, uv1. Male specific expression in 6 out of 9 CP.

• Primary Identifier: Expr15315

• Primary Identifier: Expr15316
• Pattern: acr-5 ORF

0 Life Stages

4 Parents

Definition	Name	Synonym	Primary Identifier
cell, which is the posterior descendent of TL.p.	TL.pp		WBbt:0007012
neuron of lumbar ganglion, left.	lumbar left ganglion neuron		WBbt:0005097
a cell that is born in a worm after hatching.	post-embryonic cell		WBbt:0007030
Neuron class of two interneuron in posterior ventral cord.	PVW		WBbt:0008438