2 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00002999 | lin-10 | C09H6.2 | Caenorhabditis elegans |
WBGene00004273 | rab-10 | T23H2.5 | Caenorhabditis elegans |
Primary Identifier | Expr8330 | Remark | Picture: Figure 7. |
Subcellular Localization | In the intestinal epithelia of C. elegans, RAB-10 associates with Golgi, and it is localized mainly to early endosomes. Like LIN-10, RFP::RAB-10 is present in neuronal cell bodies as well as throughout the ventral nerve cord neurites. However, unlike LIN-10::GFP, which localizes to relatively small, uniform puncta in neurites, RFP::RAB-10 localization is somewhat irregular with regard to the size and shape of clusters. Generally, RFP::RAB-10-containing clusters were less abundant and larger than LIN-10::GFP-containing clusters. Close association between RFP::RAB-10 and LIN-10::GFP was sometimes observed in neurites, as indicated by partial overlap between LIN-10::GFP and RFP::RAB-10 clusters. ~20% of LIN-10::GFP puncta were associated with a cluster of RFP::RAB-10, whereas ~40% of RFP::RAB-10 clusters were associated with one or more LIN-10::GFP puncta. While only ~5% of GLR-1::GFP clusters associated with RFP::RAB-10 clusters, and ~10% of RFP::RAB-10 clusters associated with GLR-1::GFP. These findings indicate that RAB-10 and LIN-10 are largely present at distinct compartments. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00002999 | lin-10 | C09H6.2 | Caenorhabditis elegans |
WBGene00004273 | rab-10 | T23H2.5 | Caenorhabditis elegans |