3 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003166 | mec-2 | F14D12.4 | Caenorhabditis elegans |
| WBGene00003168 | mec-4 | T01C8.7 | Caenorhabditis elegans |
| WBGene00003169 | mec-5 | E03G2.3 | Caenorhabditis elegans |
| Primary Identifier | Expr8328 | Remark | Picture: Fig 1, Fig 2. |
| Subcellular Localization | All three antibodies labeled TRN cell bodies and discrete puncta along the length of TRN neurites. MEC-2 and MEC-4 interpunctum intervals had similar distributions, including a significant proportion of intervals that were longer than 2 um. The distribution of MEC-5 intervals was more compact and no interval was longer than 2 um. On average, MEC-2 and MEC-4 IF puncta were separated by 2.6 +/-2.7 um (n = 498 intervals) and 1.7 +/- 1.9 m (n = 386 intervals), respectively, whereas MEC-5 IF puncta were separated by only 0.65 +/- 0.6 m (n = 421 intervals). Double-labeling experiments revealed that, whereas MEC-2 and MEC-4 IF puncta were colocalized, MEC-2 and MEC-5 IF puncta frequently occupied distinct domains of lateral neurites. Samples colabeled with polyclonal antibodies raised against MEC-2 in mouse and rabbit served as a control for the values expected for colocalized proteins. This analysis strongly supports the conclusion that MEC-2 colocalizes with MEC-4 but not with MEC-5. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003166 | mec-2 | F14D12.4 | Caenorhabditis elegans |
| WBGene00003168 | mec-4 | T01C8.7 | Caenorhabditis elegans |
| WBGene00003169 | mec-5 | E03G2.3 | Caenorhabditis elegans |
