| Pattern | Imaging this strain revealed significant differences in SNT-1 isoform expression and localization. The SNT-1A isoform is abundantly expressed in most neurons, and the distribution of this isoform is synaptic, resembling that of the endogenous SNT-1 (see Expr334). In contrast, the SNT-1B isoform is expressed at lower levels and in fewer neurons than SNT-1A. Many neurons express both SNT-1A and -1B, although the relative amount of each isoform varies greatly between individual cells, and some neurons appear to express only the SNT-1A isoform. Strong exclusive expression of the SNT-1B isoform was also observed in a single ventral cell located just anterior to the terminal bulb of the pharynx; which might be the excretory duct cell. In addition, SNT-1B is strongly expressed in a cluster of tail neurons, including DVB. | Primary Identifier | Expr8300 |
| Remark | Picture: Figure 3. | Reporter Gene | [snt-1::SNT-1A::CFP; snt-1::SNT-1B::YFP]. SNT-1A::CFP and SNT-1B::YFP transgenes were integrated separately, and a strain containing both integrated transgenes was constructed. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| neuron with its cell body situated in the tail, posterior to rectum. | tail neuron | WBbt:0006759 | |
| The extracellular sinus formed by the excretory duct and pore cells. | Excretory duct | WBbt:0005777 | |
| Neuron class of one ring interneuron, cell body in dorsorectal ganglion, inervates rectal muscles. | DVB | lineage name: K.p | WBbt:0004822 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004921 | snt-1 | F31E8.2 | Caenorhabditis elegans |
