WormMine: ExpressionPattern Expr8182

• Pattern: Six head neurons expressed lag-2::GFP specifically at the onset of and throughout the dauer stage. The same level of lag-2::GFP expression was observed in dauer larvae induced by dauer pheromone, starvation, or by Daf-c mutations in the three known parallel pathways, suggesting that lag-2 expression is activated downstream of the three major signalling pathways involved in dauer formation. Moreover, authors did not detect any change in the expression level of the lag-2::GFP transgene between newly induced (4 hours post-induction), and older (96 hours post-induction) dauers, suggesting that the expression of the Notch ligand is sustained throughout the dauer stage.
• Primary Identifier: Expr8182
• Remark: Picture: Figure 1A, 1B. Reporter gene fusion type not specified.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Inner labial neuron	IL2VL	lineage name: ABalppapppp	WBbt:0004538
Inner labial neuron	IL2VR	lineage name: ABarapppppp	WBbt:0004537
Inner labial neuron	IL2DL	lineage name: ABalapappap	WBbt:0004545
Inner labial neuron	IL2DR	lineage name: ABalappppap	WBbt:0004543
Inner labial neuron	IL2L	lineage name: ABalapaappp	WBbt:0004541
Inner labial neuron	IL2R	lineage name: ABalaappppp	WBbt:0004539

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002246	lag-2	Y73C8B.4	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	A third stage larva specialized for dispersal and long term survival.		dauer larva Ce	WBls:0000032