WormMine: ExpressionPattern Expr9341

• Primary Identifier: Expr9341
• Subcellular Localization: HMP-1 expression: Before morphogenesis and tissue differentiation, the HMP-1 antiserum stains all blastomeres of embryos. HMP-1 antiserum prominently labels all regions of contact between blastomeres, in addition to showing diffuse cytoplasmic staining. At approximately the time adherens junctions begin to form in the hypodermis, HMP-1 protein accumulates to high levels along the apical margins of all hypodermal cells (all hypodermal staining lies within a 1-um focal plane near the cell surface). During migration of ventral hypodermal cells, HMP-1 antiserum staining is not detected at the leading edges of these cells. HMP-1 becomes localized to the ventral margins of these cells as they contact contralateral cells at the ventral midline. During body elongation, the HMP-1 antiserum stains predominantly the apical margins of all hypodermal, pharyngeal, and intestinal cells, as does the mAbMH27 antiserum. The staining of these two antisera appears to colocalize, strongly suggesting that HMP-1 is a component of the adherens junctions. In later stages, staining appeared most prominent on the margins of the hypodermal cells that abut the two ends of the CFBs.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
	pharyngeal cell		WBbt:0005460
primary cell type that forms the hypodermis.	hypodermal cell		WBbt:0007846
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm.	intestinal cell		WBbt:0005792

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001978	hmp-1	R13H4.4	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003