WormMine: ExpressionPattern Expr1743

• Pattern: Bright fluorescence indicative of kin-18 promoter activity was observed in the pharynx, intestine, and a structure near the anus likely to be the anal sphincter. In addition, the H-shaped or excretory cell and several ring neurons also demonstrated kin-18 promoter activity. In the pharynx, cells with kin-18 promoter activity include the pharyngeal muscle of the metacorpus, the isthmus, and the terminal bulb. The pharynge-intestinal valve between the pharynx and intestine also exhibited kin-18 promoter activity.
• Primary Identifier: Expr1743
• Remark: Worms expressing lacZ with a nuclear localization signal from the kin-18 promoter corroborated the GFP expression pattern observed.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A group of six equivalent cells forms a tightly constructed `valve` that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine.	pharyngeal-intestinal valve	cardia	WBbt:0005767
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
type of cells that make up muscle layers in the pharynx.	pharyngeal muscle cell		WBbt:0005451
a saddle-shaped muscle cell that encircles the intestinal-rectal valve	anal sphincter muscle	lineage name: ABprpppppap	WBbt:0005798
H-shaped cell associated with the excretory system, largest cell in C. elegans.	excretory cell	excretory canal cell	WBbt:0005812
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002201	kin-18	T17E9.1	Caenorhabditis elegans

0 Life Stages