WormMine: ExpressionPattern Expr1444

• Pattern: Between the 2-cell and 28-cell stages of embryogenesis, equal levels of POP-1 staining were detected in sister cells born from transverse cleavages. However, different levels of POP-1 stained in almost all pairs of sister cells resulting from an a/p cleavage. For example, in the AB lineage there are no POP-1 differences after the first two divisions, which are transverse, but there are differences after the third division, which is a/p. After the first a/p division in the AB lineage, as well as after a/p divisions in other lineages, authors invariably see higher levels of staining in the nucleus of the anterior sister than in the nucleus of its posterior sister. POP-1 asymmetry appears in interphase nuclei, then POP-1 staining diminishes and is not observed in prophase nuclei. The only anterior cell in which authors fail to detect POP-1 is the P4 blastomere. Heterogeneity in POP-1 staining is observed between many neighboring nuclei in embryos after the 28-cell stage. The descendants of the E lineage can be identified readily in fixed embryos at all stages; POP-1 asymmetry was found after the first, third, and fourth divisions of the E lineage, which are a/p. The second division of the E lineage is transverse (left/right), and symmetrical levels of POP-1 were found in both pairs of sister blastomeres. In late-stage embryos, POP-1 is prominent in the developing nervous system but absent from some other tissues like the hypodermis. In larvae during postembryonic development, POP-1 is present in the row of hypodermal cells, called seam cells, along the lateral surfaces of the body. POP-1 asymmetry is observed after the seam cells divide a/p; in each pair of sisters, POP-1 appears at higher levels in the anterior sister than in the posterior sister. In addition, POP-1 is detected in migratory cells called the Q neuroblasts and in the developing gonad and vulva.
• Primary Identifier: Expr1444
• Remark: No detailed description on cellular expression pattern at later stages.
• Subcellular Localization: nucleus

12 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
adult vulval toroid cell, F, formed by fusion of precursors of lineage names P6.papl, P6.papr, P6.ppal and P6.ppar.	vulF		WBbt:0006768
adult vulval toroid cell, E, formed by fusion of precursors of lineage names P6.paal, P6.paar, P6.pppl and P6.pppr.	vulE		WBbt:0006767
organ producing either sperm or ova.	gonad		WBbt:0005175
adult vulval toroid cell, C, formed by fusion of precursors of lineage names P5.ppal, P5.ppar, P7.papl and P7.papr.	vulC		WBbt:0006765
adult vulval toroid cell, D, formed by fusion of precursors of lineage names P5.ppp and P7.paa.	vulD		WBbt:0006766
adult vulval toroid cell, B2.	vulB2		WBbt:0006764
adult vulval toroid cell, B1, formed by fusion of precursors of lineage names P5.papa and P7.ppap.	vulB1		WBbt:0006763
adult vulval toroid cell, A, formed by fusion of precursors of lineage names P5.paaa, P5.paap, P7.pppa and P7.pppp	vulA		WBbt:0006762
Postembryonic neuroblast, migrates posteriorly.	QL	lineage name: ABplapapaaa	WBbt:0004056
Postembryonic neuroblast, migrates anteriorly.	QR	lineage name: ABprapapaaa	WBbt:0004054

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004077	pop-1	W10C8.2	Caenorhabditis elegans

5 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003