WormMine: ExpressionPattern Expr2913

• Pattern: MH33 reactivity in the adult worm is completely restricted to the central region of the intestine, apparently surrounding the intestinal lumen. This is seen more clearly with the isolated adult intestine: MH33 reacts with a tubular structure that can often be seen protruding from the cut end of a dissected intestine where the gut cell cytoplasm has apparently dissociated. This structure presumably corresponds to the ``endotube'' described in the intestines of many larger nematodes. Immunoelectron microscopy shows that MH33 reacts exclusively with a discrete circumferential layer within the terminal web, closely underlying the intestinal microvillar brush border. The MH33 reactive layer continues directly into the electron dense regions that define the CeAJ and that join adjacent gut cells.
• Primary Identifier: Expr2913
• Remark: MH33 antigen = ifb-2

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002054	ifb-2	F10C1.7	Caenorhabditis elegans

0 Life Stages