WormMine: ExpressionPattern Expr574

• Pattern: PIE-1 protein is localized to the posterior of the zygote and continues to be observed in the germ line P1 through P4 and Z2 and Z3, but not in somatic blastomeres.
• Primary Identifier: Expr574
• Remark: early embryo(author) = blastula embryo(curator).
• Subcellular Localization: PIE-1 is associated with P granules in germline blastomere cytoplasm. At mitosis, PIE-1 accumulates around the centrosomes of the spindle and PIE-1 decreases in the cytoplasm. PIE-1 staining remains only in the germline blastomeres after division. After P4 divides, PIE-1 persists in both Z2 and Z3 centrosomes.

8 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
Single cell zygote	P0	lineage name: Z	WBbt:0004422
embryonic founder cell	Psub3	lineage name: P0.ppp	WBbt:0006875
embryonic founder cell	Psub1	lineage name: P0.p	WBbt:0006874
embryonic founder cell	Psub2	lineage name: P0.pp	WBbt:0006873
Embryonic founder cell of germ line	Psub4	lineage name: P0.pppp	WBbt:0004421
Germ line precursor cell	Z2	lineage name: P4.p	WBbt:0004576
Germ line precursor cell	Z3	lineage name: P4.a	WBbt:0004575

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004027	pie-1	Y49E10.14	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation.		blastula embryo Ce	WBls:0000005