WormMine: ExpressionPattern Expr578

• Pattern: Antibody staining is first detected at the bend of the reflexed hermaphrodite gonad. PAR-1 is seen in newly formed, but not mature oocytes nor newly fertilized zygotes. PAR-1 reappears in the late zygote, when both pronuclei are decondensed and the female pronucleus is just starting to migrate toward the posterior. In P0 through P3, it is localized in the posterior periphery so that it is distributed to the germ line blastomeres. When P4 divides, PAR-1 is distributed evenly and distributed to both Z2 and Z3. After P4 divides, PAR-1 gradually fades until it disappears at morphogenesis.
• Primary Identifier: Expr578
• Remark: early embryo(author) = blastula + gastrulating embryo(curator).
• Subcellular Localization: PAR-1 is membrane-associated. In dividing cells, it is restricted to the posterior until P4 divides, at which time it is located throughout the periphery. PAR-1 co-localizes with P granules.

9 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
a female haploid germ cell.	oocyte	ovum	WBbt:0006797
Single cell zygote	P0	lineage name: Z	WBbt:0004422
embryonic founder cell	Psub3	lineage name: P0.ppp	WBbt:0006875
embryonic founder cell	Psub1	lineage name: P0.p	WBbt:0006874
embryonic founder cell	Psub2	lineage name: P0.pp	WBbt:0006873
Embryonic founder cell of germ line	Psub4	lineage name: P0.pppp	WBbt:0004421
Germ line precursor cell	Z2	lineage name: P4.p	WBbt:0004576
Germ line precursor cell	Z3	lineage name: P4.a	WBbt:0004575

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003916	par-1	H39E23.1	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The C. elegans life stage spanning 100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation.		gastrulating embryo Ce	WBls:0000010
	The C. elegans life stage spanning 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage until the start of gastrulation.		blastula embryo Ce	WBls:0000005