WormMine: ExpressionPattern Expr13419

• Pattern: Transgenic lines containing stably integrated transgenes expressing an N-terminus fusion of 3FLAG::GFP to XND-1 showed identical expression patterns to that of immunostaining [Expr13418]; GFP was discernible only in the PGCs during embryonic development, expression persisted exclusively in the germline nuclei throughout larval development, and adult expression was observed in the mitotic zone through the late pachytene region with an autosomal bias (Wagner et al., 2010). XND-1 protein abruptly disappears from the late pachytene region and remains absent in mature oocytes and sperm. No somatic expression was observed with the transgenes or by immunostaining, confirming our prior conclusion from genetic studies that xnd-1 function appears limited to the germ line (Wagner et al., 2010).
• Primary Identifier: Expr13419

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
member of a set of two cells that generate exclusively sperm and ovum.	germline precursor cell	PGC	WBbt:0006849

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001514	xnd-1	C05D2.5	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023