WormMine: ExpressionPattern Expr10609

• Pattern: ZFP-1::GFP was expressed in somatic cells at all developmental stages of C. elegans. High expression in oocytes and lower expression in the distal germline was observed.Immunostaining showed high expression in maturing oocyte nuclei and lower expression in the rest of the germline. The long isoform of the protein is expressed in the germline, while the short isoform is not. The immunostaining results are consistent with the expression patterns of the short and long isoforms of ZFP-1 determined by western, where the long isoform is predominantly expressed in embryos and in adult worms with developed germline tissue and the short isoform more abundant at the larval stages. The authors conclude that only the long ZFP-1 isoform is expressed in the germline and localizes to chromosomes there.
• Primary Identifier: Expr10609
• Subcellular Localization: Consistent with immunostaining, ZFP-1::GFP localization is seen at the condensed chromosomes in oocytes; the ZFP-1::GFP protein binds to all six condensed chromosomes. The authors conclude that only the long ZFP-1 isoform is expressed in the germline and localizes to chromosomes there.

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
a female haploid germ cell.	oocyte	ovum	WBbt:0006797

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006975	zfp-1	F54F2.2	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023